Functional zwitterionic biomaterials for administration of insulin

被引:21
作者
Chen, Xingyu [1 ]
Yang, Dongqiong [1 ]
机构
[1] Southwest Jiaotong Univ, Coll Med, Chengdu 610031, Peoples R China
基金
中国国家自然科学基金;
关键词
AMYLOID FIBRIL FORMATION; POLYMER ALLOY MEMBRANE; TERM GLYCEMIC CONTROL; THIOFLAVIN-T-BINDING; PROTEIN AGGREGATION; TRANSDERMAL DELIVERY; CONTROLLED-RELEASE; VASCULAR-DISEASE; BETA-CELLS; INHIBITION;
D O I
10.1039/d0bm00986e
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Insulin administration is necessary for patients with type 1 diabetes and advanced type 2 diabetes. However, there are many drawbacks associated with it, such as hypoglycemia and loss of insulin activity. Zwitterions with antifouling, nonthrombogenic, and cell-compatible properties have attracted wide scientific interest, particularly in biomedical applications. This review focuses on the application of functional zwitterionic materials for a variety of modes of insulin administration including controlled insulin release systems, improving insulin activity, and encapsulation of islet cells. In particular, the relationships between the function of zwitterionic materials and the administration of insulin are discussed in detail. Finally, the challenges and future of zwitterionic materials in the administration of insulin are summarized.
引用
收藏
页码:4906 / 4919
页数:14
相关论文
共 151 条
[81]   A zwitterionic polymer as a novel inhibitor of protein aggregation [J].
Rajan, Robin ;
Matsumura, Kazuaki .
JOURNAL OF MATERIALS CHEMISTRY B, 2015, 3 (28) :5683-5689
[82]   Immunogenicity of therapeutic proteins: Influence of aggregation [J].
Ratanji, Kirsty D. ;
Derrick, Jeremy P. ;
Dearman, Rebecca J. ;
Kimber, Ian .
JOURNAL OF IMMUNOTOXICOLOGY, 2014, 11 (02) :99-109
[83]   A Collagen Based Cryogel Bioscaffold that Generates Oxygen for Islet Transplantation [J].
Razavi, Mehdi ;
Primavera, Rosita ;
Kevadiya, Bhavesh D. ;
Wang, Jing ;
Buchwald, Peter ;
Thakor, Avnesh S. .
ADVANCED FUNCTIONAL MATERIALS, 2020, 30 (15)
[84]   Therapeutic protein aggregation: mechanisms, design, and control [J].
Roberts, Christopher J. .
TRENDS IN BIOTECHNOLOGY, 2014, 32 (07) :372-380
[85]  
Sarah G. R., 2004, DIABETES CARE, V27, P1047
[86]   Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies [J].
Sarwar, N. ;
Gao, P. ;
Seshasai, S. R. Kondapally ;
Gobin, R. ;
Kaptoge, S. ;
Di Angelantonio, E. ;
Ingelsson, E. ;
Lawlor, D. A. ;
Selvin, E. ;
Stampfer, M. ;
Stehouwer, C. D. A. ;
Lewington, S. ;
Pennells, L. ;
Thompson, A. ;
Sattar, N. ;
White, I. R. ;
Ray, K. K. ;
Danesh, J. ;
Tipping, R. W. ;
Ford, C. E. ;
Pressel, S. L. ;
Folsom, A. R. ;
Chambless, L. E. ;
Wagenknecht, L. E. ;
Panagiotakos, D. B. ;
Pitsavos, C. ;
Chrysohoou, C. ;
Stefanadis, C. ;
Knuiman, M. ;
Whincup, P. H. ;
Wannamethee, S. G. ;
Morris, R. W. ;
Kiechl, S. ;
Willeit, J. ;
Oberhollenzer, F. ;
Mayr, A. ;
Wald, N. ;
Ebrahim, S. ;
Yarnell, J. W. ;
Gallacher, J. ;
Casiglia, E. ;
Tikhonoff, V. ;
Nietert, P. J. ;
Sutherland, S. E. ;
Bachman, D. L. ;
Keil, J. E. ;
de Boer, I. H. ;
Kizer, J. R. ;
Mukamal, K. J. ;
Tybjaerg-Hansen, A. .
LANCET, 2010, 375 (9733) :2215-2222
[87]   Glycaemic control in diabetic rats treated with islet transplantation using plasma combined with hydroxypropylmethyl cellulose hydrogel [J].
Schaschkow, Anais ;
Sigrist, Severine ;
Mura, Carole ;
Barthes, Julien ;
Vrana, Nihal Engin ;
Czuba, Elodie ;
Lemaire, Florent ;
Neidl, Romain ;
Dissaux, Caroline ;
Lejay, Anne ;
Lavalle, Philippe ;
Bruant-Rodier, Catherine ;
Bouzakri, Karim ;
Pinget, Michel ;
Maillard, Elisa .
ACTA BIOMATERIALIA, 2020, 102 :259-272
[88]   Effect of Carbon Spacer Length on Zwitterionic Carboxybetaines [J].
Shao, Qing ;
Jiang, Shaoyi .
JOURNAL OF PHYSICAL CHEMISTRY B, 2013, 117 (05) :1357-1366
[89]   Comparative Study of Protein Aggregation Arrest by Zwitterionic Polysulfobetaines: Using Contrasting Raft Agents [J].
Sharma, Neha ;
Rajan, Robin ;
Makhaik, Sparsh ;
Matsumura, Kazuaki .
ACS OMEGA, 2019, 4 (07) :12186-12193
[90]   Global estimates of the prevalence of diabetes for 2010 and 2030 [J].
Shaw, J. E. ;
Sicree, R. A. ;
Zimmet, P. Z. .
DIABETES RESEARCH AND CLINICAL PRACTICE, 2010, 87 (01) :4-14