Water-soluble gold nanoclusters with pH-dependent fluorescence and high colloidal stability over a wide pH range via co-reduction of glutathione and citrate

被引：45

作者：

Ding, Wenchao ^{[1
]}

Liu, Yong ^{[1
]}

Li, Yijing ^{[1
]}

Shi, Qiurong ^{[1
]}

Li, Houshen ^{[1
]}

Xia, Haibing ^{[1
]}

Wang, Dayang ^{[2
]}

Tao, Xutang ^{[1
]}

机构：

[1] Shandong Univ, State Key Lab Crystal Mat, Jinan 250100, Peoples R China

[2] Univ S Australia, Ian Wark Res Inst, Adelaide, SA 5095, Australia

来源：

RSC ADVANCES | 2014年 / 4卷 / 43期

基金：

澳大利亚研究理事会;

关键词：

QUASI-SPHERICAL GOLD; ONE-POT SYNTHESIS; SILVER NANOPARTICLES; SELECTIVE DETECTION; FACILE PREPARATION; QUANTUM DOTS; CLUSTERS; COMPLEXES; NANOCRYSTALS; LUMINESCENCE;

D O I：

10.1039/c4ra03363a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present a strategy for the synthesis of water-soluble, monodisperse, highly fluorescent gold nanoclusters (Au NCs) with sizes of 1.8 nm by co-reduction of glutathione and citrate (denoted as GS/C-Au NCs) for 24 h at 50 degrees C. The high content of Au(I)-thiolate complexes (about 75%) on the surfaces of core-shell structured GS/C-Au NCs is responsible for their strong fluorescence generated by aggregation-induced emission (AIE). The advantages of this method using citrate are as follows: (i) lower reaction temperature; (ii) controlled formation rate of Au(0) cores by selective reduction of Au(III) ions; and (iii) enhanced colloidal stability of GS/C-Au NCs in the wide pH range from 4.1 to 8.6 due to differently stable states of glutathione-citrate complex on the surfaces. In addition, the fluorescence intensity of GS/C-Au NCs obtained is pH-dependent and can be reversibly adjusted in the pH range from 4.1 to 8.6 due to changes in their surface charge density stemming from the transitions among differently stable states of the glutathione-citrate complex. Our preliminary study also demonstrates that the resulting GS/C-Au NCs can be used as fluorescent nanoprobes in bio-imaging.

引用

页码：22651 / 22659

页数：9