Outlooks on Three-Dimensional Printing for Ocular Biomaterials Research

被引:16
|
作者
Fenton, Owen S. [1 ]
Paolini, Marion [1 ]
Andresen, Jason L. [1 ,2 ]
Mueller, Florence J. [1 ]
Langer, Robert [1 ,3 ,4 ,5 ]
机构
[1] MIT, Koch Inst Integrat Canc Res, 77 Massachusetts Ave, Cambridge, MA 02139 USA
[2] MIT, Dept Chem, Cambridge, MA 02139 USA
[3] MIT, Dept Chem Engn, Cambridge, MA 02142 USA
[4] MIT, Inst Med Engn & Sci, 77 Massachusetts Ave, Cambridge, MA 02139 USA
[5] MIT, Harvard & MIT Div Hlth Sci & Technol, 77 Massachusetts Ave, Cambridge, MA 02139 USA
关键词
3-dimensional (3D) printing; biomaterials; tissue engineering; bioprinting; ocular research; TISSUE; FUTURE; FABRICATION; COLLAGEN; TRANSPLANTATION; RECONSTRUCTION; CHALLENGES; SCAFFOLDS; HYDROGELS;
D O I
10.1089/jop.2018.0142
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Given its potential for high-resolution, customizable, and waste-free fabrication of medical devices and in vitro biological models, 3-dimensional (3D) bioprinting has broad utility within the biomaterials field. Indeed, 3D bioprinting has to date been successfully used for the development of drug delivery systems, the recapitulation of hard biological tissues, and the fabrication of cellularized organ and tissue-mimics, among other applications. In this study, we highlight convergent efforts within engineering, cell biology, soft matter, and chemistry in an overview of the 3D bioprinting field, and we then conclude our work with outlooks toward the application of 3D bioprinting for ocular research in vitro and in vivo.
引用
收藏
页码:7 / 17
页数:11
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