Daily versus intermittent application of high-concentration tacalcitol ointment in combination with low-dose cyclosporin for psoriasis vulgaris

被引：12

作者：

Abe, Masatoshi ^{[1
]}

Syuto, Tomoko ^{[1
]}

Hasegawa, Michiko ^{[1
]}

Sogabe, Yoko ^{[1
]}

Yokoyama, Yoko ^{[1
]}

Ishikawa, Osamu ^{[1
]}

机构：

[1] Gunma Univ, Grad Sch Med, Dept Dermatol, Maebashi, Gumma 3718511, Japan

来源：

JOURNAL OF DERMATOLOGY | 2006年 / 33卷 / 02期

关键词：

cyclosporin; high-concentrated tacalcitol; intermittent application; psoriasis vulgaris;

D O I：

10.1111/j.1346-8138.2006.00022.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

In this study, we aimed to compare the clinical effectiveness of highly-concentrated tacalcitol ointment daily versus intermittent application in patients with psoriasis vulgaris who simultaneously took a low dose of cyclosporin. All the patients in both groups showed significant improvements, and the patients in the intermittent application group obtained more patient satisfaction in cost performance. The treatment cost of low-dose cyclosporin and intermittent application of highly-concentrated tacalcitol ointment was less than half of that of high-dose cyclosporin and daily application of highly-concentrated tacalcitol ointment. This preliminary study suggests that the combination therapy with low-dose cyclosporin administration and intermittent application of highly-concentrated tacalcitol is effective, safe and provides acceptable costs for the treatment.

引用

页码：108 / 111

页数：4

共 5 条

[1] High-concentration (20 μg/g) tacalcitol ointment therapy on refractory psoriasis vulgaris with low response to topical corticosteroids
Katayama, I
Ohkawara, A
Ohkido, M
Harada, S
Tamaki, K
Nakagawa, H
Hori, Y
Nishiyama, S
EUROPEAN JOURNAL OF DERMATOLOGY, 2002, 12 (06) : 553 - 557
[2] Long-term safety and efficacy of high-concentration (20 μg/g) tacalcitol ointment in psoriasis vulgaris
Miyachi, Y
Ohkawara, A
Ohkido, M
Harada, S
Tamaki, K
Nakagawa, H
Hori, Y
Nishiyama, S
EUROPEAN JOURNAL OF DERMATOLOGY, 2002, 12 (05) : 463 - 468
[3] Efficacious treatment of psoriasis with low-dose and intermittent cyclosporin microemulsion therapy
Ito, Taisuke
Furukawa, Fukumi
Iwatsuki, Keiji
Matsue, Hiroyuki
Shimada, Shinji
Takigawa, Masahiro
Tokura, Yoshiki
JOURNAL OF DERMATOLOGY, 2014, 41 (05) : 377 - 381
[4] Clinical usefulness and patient satisfaction for treatment with low-dose cyclosporin administration in patients with moderate psoriasis vulgaris
Abe, Masatoshi
Ishibuchi, Hirohisa
Syuto, Tomoko
Sogabe, Yoko
Yokoyama, Yoko
Ishikawa, Osamu
JOURNAL OF DERMATOLOGY, 2007, 34 (05) : 290 - 293
[5] Efficacy and safety of preprandial versus postprandial administration of low-dose cyclosporin microemulsion (Neoral) in patients with psoriasis vulgaris
Hashizume, Hideo
Ito, Taisuke
Yagi, Hiroaki
Takigawa, Masahiro
Kageyama, Hazuki
Furukawa, Fukiko
Hata, Maki
Shirahama, Shigeho
Tanaka, Masato
Higashishiba, Teruomi
Machida, Hideki
Tsushima, Tomoo
Matsushita, Kayo
JOURNAL OF DERMATOLOGY, 2007, 34 (07) : 430 - 434

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