Clinical course and risk factors for mortality of COVID-19 patients with pre-existing cirrhosis: a multicentre cohort study

被引：84

作者：

Qi, Xiaolong ^{[1
]}

Liu, Yanna ^{[1
]}

Wang, Jitao ^{[2
]}

Fallowfield, Jonathan A. ^{[3
]}

Wang, Jianwen ^{[4
]}

Li, Xinyu ^{[5
]}

Shi, Jindong ^{[6
]}

Pan, Hongqiu ^{[7
]}

Zou, Shengqiang ^{[7
]}

Zhang, Hongguang ^{[7
]}

Chen, Zhenhuai ^{[8
]}

Li, Fujian ^{[8
]}

Luo, Yan ^{[9
]}

Mei, Mei ^{[9
]}

Liu, Huiling ^{[9
]}

Wang, Zhengyan ^{[10
]}

Li, Jinlin ^{[10
]}

Yang, Hua ^{[11
]}

Xiang, Huihua ^{[12
]}

Li, Xiaodan ^{[13
]}

Liu, Tao ^{[14
]}

Zheng, Ming-Hua ^{[15
]}

Liu, Chuan ^{[1
]}

Huang, Yifei ^{[1
]}

Xu, Dan ^{[1
]}

Li, Xiaoguo ^{[1
]}

Kang, Ning ^{[1
]}

He, Qing ^{[16
]}

Gu, Ye ^{[17
]}

Zhang, Guo ^{[18
]}

Shao, Chuxiao ^{[19
,20
]}

Liu, Dengxiang ^{[2
]}

Zhang, Lin ^{[21
]}

Li, Xun ^{[22
]}

Kawada, Norifumi ^{[23
]}

Jiang, Zicheng ^{[24
]}

Wang, Fengmei ^{[25
]}

Xiong, Bin ^{[26
]}

Takehara, Tetsuo ^{[27
]}

Rockey, Don C. ^{[28
]}

机构：

[1] First Hosp Lanzhou Univ, Inst Portal Hypertens, CHESS Ctr, Lanzhou 730000, Peoples R China

[2] Xingtai Peoples Hosp, CHESS COVID 19 Grp, Xingtai, Peoples R China

[3] Univ Edinburgh, MRC Ctr Inflammat Res, Ctr Inflammat Res, Edinburgh, Midlothian, Scotland

[4] Wuhan Jinyintan Hosp, Dept TB & Resp, Wuhan, Peoples R China

[5] Fudan Univ, Shanghai Peoples Hosp 5, Dept Infect Dis, Shanghai, Peoples R China

[6] Fudan Univ, Shanghai Peoples Hosp 5, Dept Resp Med, Shanghai, Peoples R China

[7] Jiangsu Univ, Affiliated Hosp 3, Dept Infect Dis & Crit Care Med, Zhenjiang, Jiangsu, Peoples R China

[8] Peoples Hosp Baoding, Dept Resp Med, Baoding, Peoples R China

[9] Tianjin Haihe Hosp, Dept Gastroenterol, Tianjin, Peoples R China

[10] Hubei Univ Med, Suizhou Hosp, Dept Resp Med, Suizhou, Peoples R China

[11] Hubei Univ Nationalities, Minda Hosp, Dept Resp Med, Enshi, Peoples R China

[12] Hubei Univ Nationalities, Minda Hosp, Dept Radiol, Enshi, Peoples R China

[13] Cent Hosp Enshi Tujia & Miao Autonomous Prefectur, Dept Infect Dis, Enshi, Peoples R China

[14] Cent Hosp Lichuan, Dept Infect Dis, Enshi, Peoples R China

[15] Wenzhou Med Univ, Affiliated Hosp 1, Dept Hepatol, MAFLD Res Ctr, Wenzhou, Peoples R China

[16] Third Peoples Hosp Shenzhen, CHESS COVID 19 Grp, Shenzhen, Peoples R China

[17] Sixth Peoples Hosp Shenyang, CHESS COVID 19 Grp, Shenyang, Peoples R China

[18] Peoples Hosp Guangxi Zhuang Autonomous Reg, CHESS COVID 19 Grp, Nanning, Peoples R China

[19] Zhejiang Univ, Lishui Hosp, CHESS COVID 19 Grp, Lishui, Peoples R China

[20] Lishui Cent Hosp, Lishui, Peoples R China

[21] Tsinghua Univ, Beijing Tsinghua Changgung Hosp, Sch Clin Med, Hepatopancreatobiliary Ctr, Beijing, Peoples R China

[22] First Hosp Lanzhou Univ, Lanzhou, Peoples R China

[23] Osaka City Univ, Grad Sch Med, Dept Hepatol, Osaka, Japan

[24] Ankang Cent Hosp, Dept Infect Dis, Ankang, Peoples R China

[25] Tianjin Second Peoples Hosp, Dept Gastroenterol & Hepatol, Tianjin, Peoples R China

[26] Wuhan Union Hosp, Dept Radiol, Wuhan, Peoples R China

[27] Osaka Univ, Dept Gastroenterol & Hepatol, Grad Sch Med, Suita, Osaka, Japan

[28] Med Univ South Carolina, Div Gastroenterol & Hepatol, Charleston, SC USA

来源：

GUT | 2021年 / 70卷 / 02期

关键词：

D O I：

10.1136/gutjnl-2020-321666

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：433 / +

页数：4

共 10 条

[1] Outcomes of COVID-19 in 79 patients with IBD in Italy: an IG-IBD study [J].

Bezzio, Cristina ;

Saibeni, Simone ;

Variola, Angela ;

Allocca, Mariangela ;

Massari, Alessandro ;

Gerardi, Viviana ;

Casini, Valentina ;

Ricci, Chiara ;

Zingone, Fabiana ;

Amato, Arnaldo ;

Caprioli, Flavio ;

Lenti, Marco Vincenzo ;

Vigano, Chiara ;

Ascolani, Marta ;

Bossa, Fabrizio ;

Castiglione, Fabiana ;

Cortelezzi, Claudio ;

Grossi, Laurino ;

Milla, Monica ;

Morganti, Daniela ;

Pastorelli, Luca ;

Ribaldone, Davide Giuseppe ;

Sartini, Alessandro ;

Soriano, Alessandra ;

Manes, Gianpiero ;

Danese, Silvio ;

Fantini, Massimo ;

Armuzzi, Alessandro ;

Daperno, Marco ;

Fiorino, Gionata .

GUT, 2020, 69 (07) :1213-1217

[2] LIVER CIRRHOSIS IS INDEPENDENTLY ASSOCIATED WITH 90-DAY MORTALITY IN ARDS PATIENTS [J].

Gacouin, Arnaud ;

Locufier, Maxime ;

Uhel, Fabrice ;

Letheulle, Julien ;

Bouju, Pierre ;

Fillatre, Pierre ;

Le Tulzo, Yves ;

Tadie, Jean Marc .

SHOCK, 2016, 45 (01) :16-21

[3] Clinical Characteristics of Coronavirus Disease 2019 in China [J].

Guan, W. ;

Ni, Z. ;

Hu, Yu ;

Liang, W. ;

Ou, C. ;

He, J. ;

Liu, L. ;

Shan, H. ;

Lei, C. ;

Hui, D. S. C. ;

Du, B. ;

Li, L. ;

Zeng, G. ;

Yuen, K. -Y. ;

Chen, R. ;

Tang, C. ;

Wang, T. ;

Chen, P. ;

Xiang, J. ;

Li, S. ;

Wang, Jin-lin ;

Liang, Z. ;

Peng, Y. ;

Wei, L. ;

Liu, Y. ;

Hu, Ya-hua ;

Peng, P. ;

Wang, Jian-ming ;

Liu, J. ;

Chen, Z. ;

Li, G. ;

Zheng, Z. ;

Qiu, S. ;

Luo, J. ;

Ye, C. ;

Zhu, S. ;

Zhong, N. .

NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (18) :1708-1720

[4] Comorbidity and survival of Danish cirrhosis patients: A nationwide population-based cohort study [J].

Jepsen, Peter ;

Vilstrup, Hendrik ;

Andersen, Per Kragh ;

Lash, Timothy L. ;

Sorrensen, Henrik Toft .

HEPATOLOGY, 2008, 48 (01) :214-220

[5]

Li LQ, 2020, J MED VIROL, V92, P577, DOI [10.1002/jmv.25757, 10.1016/j.jnlest.2020.100045]

[6] Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis [J].

Lippi, Giuseppe ;

Plebani, Mario ;

Henry, Brandon Michael .

CLINICA CHIMICA ACTA, 2020, 506 :145-148

[7] Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy [J].

Onder, Graziano ;

Rezza, Giovanni ;

Brusaferro, Silvio .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (18) :1775-1776

[8] Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China [J].

Wang, Dawei ;

Hu, Bo ;

Hu, Chang ;

Zhu, Fangfang ;

Liu, Xing ;

Zhang, Jing ;

Wang, Binbin ;

Xiang, Hui ;

Cheng, Zhenshun ;

Xiong, Yong ;

Zhao, Yan ;

Li, Yirong ;

Wang, Xinghuan ;

Peng, Zhiyong .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (11) :1061-1069

[9] Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention [J].

Wu, Zunyou ;

McGoogan, Jennifer M. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (13) :1239-1242

[10] Liver injury in COVID-19: management and challenges [J].

Zhang, Chao ;

Shi, Lei ;

Wang, Fu-Sheng .

LANCET GASTROENTEROLOGY & HEPATOLOGY, 2020, 5 (05) :428-430

← 1 →