Ultrasound promoted greener synthesis of spiro[indole-3,5′-[1,3]oxathiolanes in water

被引：37

作者：

Dandia, Anshu ^{[1
]}

Singh, Ruby ^{[1
]}

Bhaskaran, Sumit ^{[1
]}

机构：

[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

来源：

ULTRASONICS SONOCHEMISTRY | 2010年 / 17卷 / 02期

关键词：

Spiro-oxirane; Water; Sonication; Spiro-oxathiolane; DERIVATIVES; ANALOGS; MEDIA;

D O I：

10.1016/j.ultsonch.2009.08.003

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

An aqueous mediated novel synthesis of substituted 2'amino-4'benzoyl-2'-methyl spiro[indole 3,5'-[1,3]oxathiolane]-2(1H)-ones (2a-f) was carried out from the reaction of spiro [indole-3,2'-oxiranes] (1a-f) with thioacetamide in the presence of LiBr as catalyst. The reaction was carried out under both microwaves and sonication and results were also compared with conventional method. in general, improvement in rate and yields observed when reaction was carried out under sonication as compared to microwave irradiation and conventional method. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：399 / 402

页数：4

共 53 条

[11] Microwave enhanced solid support synthesis of fluorine containing benzopyrano-triazolo-thiadiazepines as potent anti-fungal agents
Dandia, A
Singh, R
Khaturia, S
[J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2006, 14 (05) : 1303 - 1308
[12] Reinvestigation of the synthesis of 2-benzyl-3-aryl-quinazolin-4-[3H]-ones.: An improved multi-component procedure using microwaves
Dandia, A
Singh, R
Sarawgi, P
[J]. ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2005, 37 (04) : 397 - 402
[13] Green chemical multi-component one-pot synthesis of fluorinated 2,3-disubstituted quinazolin-4(3H)-ones under solvent-free conditions and their anti-fungal activity
Dandia, A
Singh, R
Sarawgi, P
[J]. JOURNAL OF FLUORINE CHEMISTRY, 2004, 125 (12) : 1835 - 1840
[14] Microwave assisted green chemical synthesis of novel spiro[indole-pyrido thiazines]: a system reluctant to be formed under thermal conditions
Dandia, A
Arya, K
Sati, M
Gautam, S
[J]. TETRAHEDRON, 2004, 60 (24) : 5253 - 5258
[15] Dry-media one-pot syntheses of fluorinated-2,3-dihydro-1,5-benzothiazepines under microwave activation
Dandia, A
Sati, M
Loupy, A
[J]. GREEN CHEMISTRY, 2002, 4 (06) : 599 - 602
[16] Dandia A, 2002, PHARMAZIE, V57, P602
[17] Efficient microwave enhanced solvent-free synthesis of potent antifungal agents:: Fluorinated benzothiazepine fused β-lactam derivatives
Dandia, Anshu
Singh, Ruby
Khaturia, Sarita
[J]. JOURNAL OF FLUORINE CHEMISTRY, 2007, 128 (05) : 524 - 529
[18] DHAKA N, 2008, THESIS RAJASTHAN U J
[19] Facile preparation of α-acyloxyacetaldehyde, a versatile intermediate in the synthesis of antiviral nucleosides
Du, JF
Watanabe, KA
[J]. SYNTHETIC COMMUNICATIONS, 2004, 34 (11) : 1925 - 1930
[20] Serine derived NK1 antagonists 2:: A pharmacophore model for arylsulfonamide binding.
Elliott, JM
Broughton, H
Cascieri, MA
Chicchi, G
Huscroft, IT
Kurtz, M
MacLeod, AM
Sadowski, S
Stevenson, GI
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (14) : 1851 - 1856

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