Ultrasound promoted greener synthesis of spiro[indole-3,5′-[1,3]oxathiolanes in water

被引：37

作者：

Dandia, Anshu ^{[1
]}

Singh, Ruby ^{[1
]}

Bhaskaran, Sumit ^{[1
]}

机构：

[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

来源：

ULTRASONICS SONOCHEMISTRY | 2010年 / 17卷 / 02期

关键词：

Spiro-oxirane; Water; Sonication; Spiro-oxathiolane; DERIVATIVES; ANALOGS; MEDIA;

D O I：

10.1016/j.ultsonch.2009.08.003

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

An aqueous mediated novel synthesis of substituted 2'amino-4'benzoyl-2'-methyl spiro[indole 3,5'-[1,3]oxathiolane]-2(1H)-ones (2a-f) was carried out from the reaction of spiro [indole-3,2'-oxiranes] (1a-f) with thioacetamide in the presence of LiBr as catalyst. The reaction was carried out under both microwaves and sonication and results were also compared with conventional method. in general, improvement in rate and yields observed when reaction was carried out under sonication as compared to microwave irradiation and conventional method. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：399 / 402

页数：4

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