Mixed Ternary Complexes of Sparfloxacin with Some Biologically Important Amino Acids

被引：0
作者：
Kamel, R. M. [1 ]
Hegazy, W. H. [1 ]
Ali, R. S. [1 ]
El-Sayed, A. A. [1 ]
机构：
[1] Suez Univ, Fac Sci, Chem Dept, Suez 43518, Egypt
来源：
JOURNAL OF SOLUTION CHEMISTRY | 2021年 / 50卷 / 03期
关键词：
Mixed complexes; Amino acids; Binding constant; Sparfloxacin; METAL-COMPLEXES; SERUM-ALBUMIN; EQUILIBRIA; COPPER(II); CONSTANTS; ZINC(II); BINDING;
D O I：
10.1007/s10953-021-01057-8
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Potentiometric measurements for the interaction of sparfloxacin (SPFX) and the metal ions Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) with the amino acids (AA) aspartic acid, alanine, valine, glutamic acid, threonine, methionine, arginine, phenylalanine were studied. The formation constants for the 1:1 binary and 1:1:1 ternary complexes in 10% (v/v) ethanol-water, I = 0.1 mol.L-1 KNO3 and 25 degrees C were measured. The values were refined using the HYPERQUAD computer program. The binding constants of M(II)-SPFX binary complexes with bovine serum albumin using absorption titration experiments were also determined.
引用
收藏
页码：340 / 354
页数：15
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