Intravenous immunoglobulin therapy for Miller Fisher syndrome

被引:111
作者
Mori, Masahiro
Kuwabara, Satoshi
Fukutake, Toshio
Hattori, Takamichi
机构
[1] Chiba Univ, Grad Sch Med, Dept Neurol, Chuo Ku, Chiba 2608670, Japan
[2] Kameda Med CTr, Dept Neurol, Kamogawa, Chiba, Japan
关键词
D O I
10.1212/01.wnl.0000258673.31824.61
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We analyzed clinical recovery of 92 patients with Miller Fisher syndrome who had been treated with IV immunoglobulin (IVIg; n = 28), plasmapheresis (n = 23), and no immune treatment (n = 41). IVIg slightly hastened the amelioration of ophthalmoplegia and ataxia, but the times of the disappearances of those symptoms were similar among three groups. In Miller Fisher syndrome, IVIg and plasmapheresis seem not to have influenced patients' outcomes, presumably because of good natural recovery.
引用
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页码:1144 / 1146
页数:3
相关论文
共 10 条
[1]   THE USE OF INTRAVENOUS IMMUNOGLOBULIN IN MILLER FISHER SYNDROME [J].
ARAKAWA, Y ;
YOSHIMURA, M ;
KOBAYASHI, S ;
ICHIHASHI, K ;
MIYAO, M ;
MOMOI, MY ;
YANAGISAWA, M .
BRAIN & DEVELOPMENT, 1993, 15 (03) :231-233
[3]   Immunoglobulins inhibit pathophysiological effects of anti-GQ1b-positive sera at motor nerve terminals through inhibition of antibody binding [J].
Jacobs, BC ;
O'Hanlon, GM ;
Bullens, RWM ;
Veitch, J ;
Plomp, JJ ;
Willison, HJ .
BRAIN, 2003, 126 :2220-2234
[4]   SUCCESSFUL PLASMAPHERESIS IN THE MILLER-FISHER SYNDROME [J].
LITTLEWOOD, R ;
BAJADA, S .
BRITISH MEDICAL JOURNAL, 1981, 282 (6266) :778-778
[5]  
MCKHANN, 1985, NEUROLOGY, V35, P1096
[6]   Plasmapheresis and Miller Fisher syndrome: analysis of 50 consecutive cases [J].
Mori, M ;
Kuwabara, S ;
Fukutake, T ;
Hattori, T .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2002, 72 (05) :680-680
[7]   Clinical features and prognosis of Miller Fisher syndrome [J].
Mori, M ;
Kuwabara, S ;
Fukutake, T ;
Yuki, N ;
Hattori, T .
NEUROLOGY, 2001, 56 (08) :1104-1106
[8]   A RANDOMIZED TRIAL COMPARING INTRAVENOUS IMMUNE GLOBULIN AND PLASMA-EXCHANGE IN GUILLAIN-BARRE-SYNDROME [J].
VANDERMECHE, FGA ;
SCHMITZ, PIM .
NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (17) :1123-1129
[9]   Tryptophan-immobilized column adsorbs immunoglobulin G anti-GQ1b antibody from Fisher's syndrome: A new approach to treatment [J].
Yuki, N .
NEUROLOGY, 1996, 46 (06) :1644-1651
[10]  
ZIFKO U, 1994, J NEUROL, V241, P178