D-camphor-crataegus berry extract combination increases blood pressure and cognitive functioning in the elderly - A randomized, placebo controlled double blind study

被引：10
作者：
Werner, Natalie S. [1 ]
Duschek, Stefan [1 ]
Schandry, Rainer [1 ]
机构：
[1] Univ Munich, Dept Psychol, D-80802 Munich, Germany
来源：
PHYTOMEDICINE | 2009年 / 16卷 / 12期
关键词：
Cognitive function; Blood pressure; Camphor; Crataegus berry; Elderly women; Randomized; Placebo controlled double blind study; ORTHOSTATIC HYPOTENSION; REACTION-TIME; PERFORMANCE; ATTENTION; EXERCISE; CATECHOLAMINE; ENHANCEMENT; ACTIVATION; ELEVATION; EFFICACY;
D O I：
10.1016/j.phymed.2009.05.006
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The present study investigated whether the D-camphor-crataegus berry extract combination Korodin (R) elevates blood pressure and enhances cognitive performance in the elderly population Eighty women aged between 50 and 80 years were examined based on a randomized, placebo controlled double blind design Blood pressure was measured sphygmomanometrically and through continuous noninvasive recording. Cognitive performance was assessed by means of two tests measuring general information processing capacity and visuomotor speed. The administration of the drug led to a short term increase in blood pressure as well as in cognitive performance as compared to placebo. Potential physiological mechanisms of action mediating this effect, Including hemodynamic alterations, sympathetic stimulation as well as improvement of cerebral metabolism are discussed (C) 2009 Elsevier GmbH All rights reserved
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页码：1077 / 1082
页数：6
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