Changing Trends in Mastectomy and Breast Reconstruction. Analysis of a Single-institution Experience Between 2004-2016

被引：13

作者：

Susini, Tommaso ^{[1
]}

Renda, Irene ^{[1
]}

Giani, Milo ^{[1
]}

Vallario, Arianna ^{[1
]}

Nori, Jacopo ^{[2
]}

Vanzi, Ermanno ^{[2
]}

Innocenti, Alessandro ^{[3
]}

Lo Russo, Giulia ^{[3
]}

Bianchi, Simonetta ^{[4
]}

机构：

[1] Univ Florence, Dept Hlth Sci, Breast Unit, Gynecol Sect, Largo Brambilla 3, I-50134 Florence, Italy

[2] Azienda Ospedaliero Univ Careggi, Diagnost Senol Unit, Florence, Italy

[3] Azienda Ospedaliero Univ Careggi, Plast & Reconstruct Sugery Unit, Florence, Italy

[4] Univ Florence, Dept Hlth Sci, Pathol Unit, Florence, Italy

来源：

ANTICANCER RESEARCH | 2019年 / 39卷 / 10期

关键词：

Mastectomy; immediate reconstruction; reconstructive techniques; nipple-sparing mastectomy; breast implants; reconstruction failure; reconstruction with autologous tissues; SKIN-SPARING MASTECTOMY; ONCOLOGICAL SAFETY; RADIATION-THERAPY; CANCER; RATES; RISK;

D O I：

10.21873/anticanres.13770

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background/Aim: Recently, "conservative" mastectomy with immediate breast reconstruction (M-R) has become the gold standard when the breast must be removed. We analyzed the evolution in the choice of mastectomy type in our Unit, focusing on factors associated with renounce to reconstruction and risk factors for its failure. Patients and Methods: Clinical-pathological and surgical features of 132 patients who underwent mastectomy in our Unit from 2004 to 2016 were analyzed. M-R rate and different mastectomy techniques' rates between 2004-2009 and 2010-2016 were compared. Results: M-R was associated with younger age at diagnosis (p<0.001) and early tumor stage (p=0.03). M-R rate increased from 49.1% to 72.2% (p=0.002) in the last years, with prominent use of nipple-sparing-mastectomy (p<0.001). M-R failure rate was associated with previous or subsequent irradiation/chemotherapy in 92.3% of cases. Conclusion: M-R and particularly nipple-sparing-mastectomy represented the standard in more recent years; reconstruction failure was associated with irradiation/chemotherapy, especially in implant-based reconstructions.

引用

页码：5709 / 5714

页数：6

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