Necrotizing pneumonia by community-acquired, methicillin-resistant Staphylococcus aureus in Colombia

被引：0

作者：

Hernando Gomez, Carlos ^{[1
]}

Maria Perilla, Ana ^{[1
]}

Gonzalez, Camilo ^{[1
]}

Liliana Valderrama, Sandra ^{[1
]}

Vanegas, Natasha ^{[2
]}

Chavarro, Bibiana ^{[2
]}

Carlos Triana, Luis ^{[1
]}

Roberto Tamara, Jose ^{[1
]}

Arturo Alvarez, Carlos ^{[1
]}

机构：

[1] Pontificia Univ Javeriana, Hosp Univ San Ignacio, Bogota, DC, Colombia

[2] Univ El Bosque, Inst Genet Mol Bacteriana, Bogota, DC, Colombia

来源：

BIOMEDICA | 2009年 / 29卷 / 04期

关键词：

Staphylococcus aureus; methicillin resistance; community-acquired infections; pneumonia; staphylococcal; leukocidins; drug resistance; bacterial; renal insufficiency; acute; Colombia; VIRULENCE DETERMINANTS; MULTIPLEX PCR; USA300; CLONE; PATTERNS; GENES;

D O I：

暂无

中图分类号：

R188.11 [热带医学];

学科分类号：

摘要：

The emergence of community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) as a cause of severe infections has been described in the recent years. In 2006, the first report of skin and soft tissue infection by CA-MRSA was published in Colombia. Herein, two additional cases of CA-MRSA are reported with a clinical course characterized by rapid progression, prolonged stay in the intensive care unit and complication of pneumonia with the onset of empyema. Both adult patients developed acute renal failure, and were treated with linezolide; the subsequent clinical response showed adequate treatment response. Molecular characterization of the isolates indicated the presence of the mecA gene carrying the cassette SCCmec type IV and the production of the toxin panton-valentine leukocidin.

引用

页码：523 / 530

页数：8

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