A simple sensitive ratiometric fluorescent probe for the detection of mercury ions in living cells and zebrafish

被引：16

作者：

Yu, Yamin ^{[1
]}

Sheng, Wenlong ^{[2
]}

Liu, Caiyun ^{[1
]}

Gao, Na ^{[1
]}

Tian, Bin ^{[2
]}

Zhu, Hanchuang ^{[1
]}

Jia, Pan ^{[1
]}

Li, Zilu ^{[1
]}

Zhang, Xue ^{[1
]}

Wang, Kun ^{[1
]}

Li, Xiwei ^{[1
]}

Zhu, Baocun ^{[1
]}

机构：

[1] Univ Jinan, Sch Water Conservancy & Environm, Jinan 250022, Peoples R China

[2] Qilu Univ Technol, Shandong Acad Sci, Biol Inst, Jinan 250103, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2021年 / 249卷

基金：

中国国家自然科学基金;

关键词：

Mercaptoethanol; Ratiometric fluorescent probe; Mercury ions; Coumarin; Bioimaging; TURN-ON PROBE; RAPID DETECTION; HYPOCHLOROUS ACID; AQUEOUS-SOLUTION; STOKES SHIFT; HG2+; SELECTIVITY; POLYMER; SAMPLES; DOTS;

D O I：

10.1016/j.saa.2020.119279

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Mercury, as a highly toxic heavy metal, can cause very serious harm to human health and even death in severe cases. Therefore, we synthesized a novel ratiometric fluorescent probe for detecting mercury ions, with mercaptoethanol as the recognition receptor. Probe CMER could determine mercury ions in 0-1.6 mu M and the detection limit is 7.6 nM. Moreover, CMER manifested a fast response for Hg2+ (within 5 s) and simultaneously observed that the color changed from light yellow to orange by naked eye. In addition to these preeminent spectral properties, the probe also had satisfactory bioimaging results in RAW 264.7 macrophage cells and zebrafish. (C) 2020 Elsevier B.V. All rights reserved.

引用

页数：7

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