A simple sensitive ratiometric fluorescent probe for the detection of mercury ions in living cells and zebrafish

被引：17

作者：

Yu, Yamin ^{[1
]}

Sheng, Wenlong ^{[2
]}

Liu, Caiyun ^{[1
]}

Gao, Na ^{[1
]}

Tian, Bin ^{[2
]}

Zhu, Hanchuang ^{[1
]}

Jia, Pan ^{[1
]}

Li, Zilu ^{[1
]}

Zhang, Xue ^{[1
]}

Wang, Kun ^{[1
]}

Li, Xiwei ^{[1
]}

Zhu, Baocun ^{[1
]}

机构：

[1] Univ Jinan, Sch Water Conservancy & Environm, Jinan 250022, Peoples R China

[2] Qilu Univ Technol, Shandong Acad Sci, Biol Inst, Jinan 250103, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2021年 / 249卷

基金：

中国国家自然科学基金;

关键词：

Mercaptoethanol; Ratiometric fluorescent probe; Mercury ions; Coumarin; Bioimaging; TURN-ON PROBE; RAPID DETECTION; HYPOCHLOROUS ACID; AQUEOUS-SOLUTION; STOKES SHIFT; HG2+; SELECTIVITY; POLYMER; SAMPLES; DOTS;

D O I：

10.1016/j.saa.2020.119279

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Mercury, as a highly toxic heavy metal, can cause very serious harm to human health and even death in severe cases. Therefore, we synthesized a novel ratiometric fluorescent probe for detecting mercury ions, with mercaptoethanol as the recognition receptor. Probe CMER could determine mercury ions in 0-1.6 mu M and the detection limit is 7.6 nM. Moreover, CMER manifested a fast response for Hg2+ (within 5 s) and simultaneously observed that the color changed from light yellow to orange by naked eye. In addition to these preeminent spectral properties, the probe also had satisfactory bioimaging results in RAW 264.7 macrophage cells and zebrafish. (C) 2020 Elsevier B.V. All rights reserved.

引用

页数：7

共 47 条

[1] Boron-doped graphitic carbon nitride as a novel fluorescent probe for mercury(ii) and iron(iii): a circuit logic gate mimic [J].

Azimi, Elham Boorboor ;

Badiei, Alireza ;

Jafari, Maryam ;

Dehkordi, Ali Banitalebi ;

Ghasemi, Jahan B. ;

Ziarani, Ghodsi Mohammadi .

NEW JOURNAL OF CHEMISTRY, 2019, 43 (30) :12087-12093

[2] A two-photon fluorescent probe for colorimetric and ratiometric monitoring of mercury in live cells and tissues [J].

Chen, Liyan ;

Park, Sang Jun ;

Wu, Di ;

Kim, Hwan Myung ;

Yoon, Juyoung .

CHEMICAL COMMUNICATIONS, 2019, 55 (12) :1766-1769

[3] Homopropargyl as a new recognition moiety of a fluorescent probe for detection of palladium in living cells [J].

Chen, Miao ;

Wang, Xianhui ;

Wang, Nannan ;

Ji, Xin ;

He, Jinling ;

Zhang, Jian ;

Zhao, Weili .

ANALYTICAL METHODS, 2019, 11 (32) :4093-4098

[4] Thioacetalized coumarin-based fluorescent probe for mercury(II): ratiometric response, high selectivity and successful bioimaging application [J].

Cheng, Xiaohong ;

Qu, Shaohua ;

Xiao, Li ;

Li, Wangnan ;

He, Ping .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2018, 364 :503-509

[5] Highly selective and sensitive fluorescence reporter for toxic Hg(II) ion by a synthetic symmetrical azine derivative [J].

Dalapati, Sasanka ;

Paul, Bijan Kumar ;

Jana, Sankar ;

Guchhait, Nikhil .

SENSORS AND ACTUATORS B-CHEMICAL, 2011, 157 (02) :615-620

[6] A Coumarin-Based Fluorescent Probe for Ratiometric Monitoring of Hg2+ in Live Cells [J].

Ding, Yu ;

Pan, Yimin ;

Han, Yifeng .

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2019, 58 (19) :7786-7793

[7] A carbonothioate-based far-red fluorescent probe for the specific detection of mercury ions in living cells and zebrafish [J].

Duan, Qingxia ;

Zhu, Hanchuang ;

Liu, Caiyun ;

Yuan, Ruifang ;

Fang, Zhaotong ;

Wang, Zuokai ;

Jia, Pan ;

Li, Zilu ;

Sheng, Wenlong ;

Zhu, Baocun .

ANALYST, 2019, 144 (04) :1426-1432

[8] Near-infrared fluorogenic switches for the detection of Hg(ii) ions: applications in real samples and living cells [J].

Gomathi, Asaithambi ;

Viswanathamurthi, Periasamy .

ANALYTICAL METHODS, 2019, 11 (21) :2769-2777

[9] ESIPT Fluorescence Probe Based on Double-Switch Recognition Mechanism for Selective and Rapid Detection of Hydrogen Sulfide in Living Cells [J].

Guan, Hongwei ;

Zhang, Aixia ;

Li, Peng ;

Xia, Lixin ;

Guo, Feng .

ACS OMEGA, 2019, 4 (05) :9113-9119

[10] Fast and selective detection of mercury ions in environmental water by paper-based fluorescent sensor using boronic acid functionalized MoS2 quantum dots [J].

Guo, Xinrong ;

Huang, Jianzhi ;

Wei, Yubo ;

Zeng, Qiang ;

Wang, Lishi .

JOURNAL OF HAZARDOUS MATERIALS, 2020, 381

← 1 2 3 4 5 →