Rapid elucidation of chemical shift correlations in complex NMR spectra of organic molecules: Two-dimensional Hadamard pure shift NMR spectroscopy

被引：5

作者：

Kakita, Veera Mohana Rao ^{[1
]}

Kupce, Eriks ^{[3
]}

Bharatam, Jagadeesh ^{[4
]}

Hosur, Ramakrishna V. ^{[1
,2
]}

机构：

[1] UM, DAE Ctr Excellence Basic Sci, Kalina Campus, Bombay 400098, Maharashtra, India

[2] TIFR, Dept Chem Sci, 1 Homi Bhabha Rd, Bombay 400005, Maharashtra, India

[3] Bruker UK Ltd, Banner Lane, Coventry CV4 9GH, W Midlands, England

[4] Indian Inst Technol, CSIR, Ctr NMR & Struct Chem, Hyderabad 500007, Andhra Pradesh, India

来源：

JOURNAL OF MAGNETIC RESONANCE | 2018年 / 293卷

关键词：

Hadamard NMR; Real time pure shift NMR; Homodecoupling; Chemical shift correlation; Ultra high resolution; TOCSY EXPERIMENT; RESOLUTION; H-1-NMR; SOLIDS; SENSITIVITY; MIXTURES; BIRD; HMQC;

D O I：

10.1016/j.jmr.2018.06.006

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Novel two dimensional Hadamard encoding/decoding based pure shift NMR acquisition techniques (TOCSY and HSQC) have been developed, which provide chemical shift information at ultra high resolution in very short spectrometer times. The efficacy of these methods for rapid assignment of chemical shifts in complex NMR spectra of organic molecules/natural products has been demonstrated. This would be of great help for rapid analysis of samples during separation of complex mixtures. (C) 2018 Elsevier Inc. All rights reserved.

引用

页码：77 / 81

页数：5

共 57 条

[31] Fast multi-dimensional NMR of proteins [J].

Kupce, E ;

Freeman, R .

JOURNAL OF BIOMOLECULAR NMR, 2003, 25 (04) :349-354

[32] Recording 13C-15N HMQC 2D sparse spectra in solids in 30 s [J].

Kupce, Eriks ;

Trebosc, Julien ;

Perrone, Barbara ;

Lafon, Olivier ;

Amoureux, Jean-Paul .

JOURNAL OF MAGNETIC RESONANCE, 2018, 288 :76-83

[33] Sensitivity enhancement in slice-selective NMR experiments through polarization sharing [J].

Lokesh ;

Suryaprakash, N. .

CHEMICAL COMMUNICATIONS, 2014, 50 (62) :8550-8553

[34] Toward single-shot pure-shift solution 1H NMR by trains of BIRD-based homonuclear decoupling [J].

Lupulescu, Adonis ;

Olsen, Gregory L. ;

Frydman, Lucio .

JOURNAL OF MAGNETIC RESONANCE, 2012, 218 :141-146

[35] Adiabatic z-filtered J-spectroscopy for absorptive homonuclear decoupled spectra [J].

Luy, Burkhard .

JOURNAL OF MAGNETIC RESONANCE, 2009, 201 (01) :18-24

[36] Faster and cleaner real-time pure shift NMR experiments [J].

Mauhart, Johannes ;

Glanzer, Simon ;

Sakhaii, Peyman ;

Bermel, Wolfgang ;

Zangger, Klaus .

JOURNAL OF MAGNETIC RESONANCE, 2015, 259 :207-215

[37] Boosting the Resolution of 1H NMR Spectra by Homonuclear Broadband Decoupling [J].

Meyer, N. Helge ;

Zangger, Klaus .

CHEMPHYSCHEM, 2014, 15 (01) :49-55

[38] Simplifying Proton NMR Spectra by Instant Homonuclear Broadband Decoupling [J].

Meyer, N. Helge ;

Zangger, Klaus .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (28) :7143-7146

[39] True Chemical Shift Correlation Maps: A TOCSY Experiment with Pure Shifts in Both Dimensions [J].

Morris, Gareth A. ;

Aguilar, Juan A. ;

Evans, Robert ;

Haiber, Stephan ;

Nilsson, Mathias .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (37) :12770-12772

[40]

Moutzouri P, 2017, CHEM COMMUN, V53, P10188, DOI 10.1039/c7cc04423b

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