Polyphenols, antioxidants, and antimutagenic effects of Copaifera langsdorffii fruit

被引：44

作者：

Batista, Angela Giovana ^{[1
]}

Ferrari, Angelica Simoes

da Cunha, Debora Cristina

da Silva, Juliana Kelly ^{[1
]}

Betim Cazarin, Cinthia Bau ^{[1
]}

Correa, Luiz Claudio ^{[3
]}

Prado, Marcelo Alexandre ^{[1
]}

de Carvalho-Silva, Luciano Bruno

Esteves, Elizabethe Adriana ^{[2
]}

Marostica Junior, Mario Roberto ^{[1
]}

机构：

[1] Univ Campinas UNICAMP, Sch Food Engn, Campinas, SP, Brazil

[2] Fed Univ Vales Jequitinhonha & Mucuri UFVJM, Dept Nutr, Diamantina, MG, Brazil

[3] Embrapa Trop Semiarid, Brazilian Agr Res Corp, BR-56302970 Petrolina, Pernambuco, Brazil

来源：

FOOD CHEMISTRY | 2016年 / 197卷

基金：

巴西圣保罗研究基金会;

关键词：

Copaiba; Gallic acid; Micronuclei; Antioxidant capacity; ACID-INDUCED COLITIS; PHENOLIC-COMPOUNDS; OXIDATIVE STRESS; GALLIC ACID; OLEO-RESIN; GREEN TEA; CAPACITY; FLUORESCEIN; VALIDATION; ASSAYS;

D O I：

10.1016/j.foodchem.2015.11.093

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Copaifera langsdorffii (copaiba) is a Brazilian exotic fruit, poorly studied regarding its bioactive composition. The aim of this study was to determine bioactive compounds, antioxidant and antimutagenic activities of copaiba pulp. The samples were extracted with different solvents in order to analyze polyphenol compounds (Folin Ciocalteau and HPLC-DAD), total flavonoids (reaction with AlCl3) and antioxidant capacity (FRAP, ORAC, DPPH). The copaiba fruit showed high polyphenol content and antioxidant capacity. Phenolic compounds, such as gallic acid, epicatechin gallate, catechin, epicatechin and isoquercitrin, were identified in the copaiba pulp. Despite the antioxidant capacity, the highest dose of copaiba showed no antimutagenic effects in the in vivo study. The dose which showed antimutagenic activity was 100 mg kg(-1). (C) 2015 Published by Elsevier Ltd.

引用

页码：1153 / 1159

页数：7

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