Two Novel Zn(II) and Ag(I) Metal Complexes: Inhibiting Growth of Human Lung Cancer Cells

被引：0
作者：
Wei, Jun [1 ]
Ge, Jian-Jun [1 ]
机构：
[1] AnHui Med Univ, AnHui Prov Hosp, Dept Cardiovasc Surg, Hefei, Anhui, Peoples R China
来源：
LATIN AMERICAN JOURNAL OF PHARMACY | 2018年 / 37卷 / 06期
关键词：
coordination polymer; lung cancer; X-ray; ORGANIC FRAMEWORK;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Two new Zn(II)-based and Ag(I)-based coordination polymers, [Zn(1,3-pda)(bmib)center dot(H2O)] n [1, H(2)1,3-pda = 1,3-phenylenediacetate, bmib = 1,3-bis(2-methylimidazolyl) butane] and [Ag(bmib)(ClO4)] n (2), have been successfully synthesized and structurally characterized by single crystal X-ray analysis. In addition, in vitro cytotoxicity and anticancer activities of compounds 1 and 2 have been studied against 293 cells (Human Embryonic Kidney cells) and four human lung cancer cell lines (H1299, MSTO-211H, PC9 and A549) by MTT assay.
引用
收藏
页码：1192 / 1196
页数：5
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