Artificial metalloproteins with a ruthenium tris(bipyridyl) complex as the core

被引：23
作者：
Ishida, Hitoshi
Maruyama, Yuji
Kyakuno, Masato
Kodera, Yoshio
Maeda, Tadakazu
Oishi, Shigero
机构：
[1] Kitasato Univ, Dept Chem, Sch Sci, Sagamihara, Kanagawa 2288555, Japan
[2] Kitasato Univ, Dept Phys, Sch Sci, Sagamihara, Kanagawa 2288555, Japan
来源：
CHEMBIOCHEM | 2006年 / 7卷 / 10期
关键词：
bipyridines; metalloproteins; peptidomimetics; ruthenium; unnatural amino acids;
D O I：
10.1002/cbic.200600162
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Peptide origami. A peptide containing three residues of 5′-amino-2,2′-bipyridine-5-carboxylic acid (5 Bpy) as an unnatural amino acid has been folded by coordination with a ruthenium(II) ion to generate an artificial metalloprotein. Four isomers were separated by HPLC and identified by MALDI-TOF-MS. Each isomer was further characterized by absorption, emission, and CD spectra. © Wiley-VCH Verlag GmbH & Co. KGaA.
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页码：1567 / 1570
页数：4
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