Atomic Force Microscopy for Protein Detection and Their Physicochemical Characterization

被引：57

作者：

Pleshakova, Tatyana O. ^{[1
]}

Bukharina, Natalia S. ^{[1
]}

Archakov, Alexander I. ^{[1
]}

Ivanov, Yuri D. ^{[1
]}

机构：

[1] Inst Biomed Chem, 10 Pogodinskaya St, Moscow 119121, Russia

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2018年 / 19卷 / 04期

基金：

俄罗斯科学基金会;

关键词：

atomic force microscopy; protein fishing; protein characterization; LANGMUIR-BLODGETT-FILMS; SINGLE-MOLECULE; BIOMOLECULAR INTERACTIONS; MONOCLONAL-ANTIBODIES; DIRECT VISUALIZATION; ELECTRON-MICROSCOPY; PURPLE MEMBRANES; HIGH-RESOLUTION; DNA-MOLECULES; AFM;

D O I：

10.3390/ijms19041142

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review is focused on the atomic force microscopy (AFM) capabilities to study the properties of protein biomolecules and to detect the proteins in solution. The possibilities of application of a wide range of measuring techniques and modes for visualization of proteins, determination of their stoichiometric characteristics and physicochemical properties, are analyzed. Particular attention is paid to the use of AFM as a molecular detector for detection of proteins in solutions at low concentrations, and also for determination of functional properties of single biomolecules, including the activity of individual molecules of enzymes. Prospects for the development of AFM in combination with other methods for studying biomacromolecules are discussed.

引用

页数：18

共 140 条

[61] AFM study of cytochrome CYP102A1 oligomeric state [J].

Ivanov, Yuri D. ;

Bukharina, Natalia S. ;

Frantsuzov, Pavel A. ;

Pleshakova, Tatyana O. ;

Kanashenko, Sergey L. ;

Medvedeva, Natalia V. ;

Argentova, Viktoriya V. ;

Zgoda, Viktor G. ;

Munro, Andrew W. ;

Archakov, Alexander I. .

SOFT MATTER, 2012, 8 (17) :4602-4608

[62] Comparative investigation of PdR by usual and ultrafine atomic force microscopy [J].

Ivanov, Yuri D. ;

Frantsuzov, Pavel A. ;

Bykov, Victor A. ;

Besedin, Stanislav P. ;

Hoa, Gaston Hui Bon ;

Archakov, Alexander I. .

ANALYTICAL METHODS, 2010, 2 (06) :688-693

[63] Unfolding pathways of native bacteriorhodopsin depend on temperature [J].

Janovjak, H ;

Kessler, M ;

Oesterhelt, D ;

Gaub, H ;

Müller, DJ .

EMBO JOURNAL, 2003, 22 (19) :5220-5229

[64] Atomic force microscopy in bionanotechnology [J].

Kada, Gerald ;

Kienberger, Ferry ;

Hinterdorfer, Peter .

NANO TODAY, 2008, 3 (1-2) :12-19

[65] Combined AFM and confocal fluorescence microscope for applications in bio-nanotechnology [J].

Kassies, R ;

Van der Werf, KO ;

Lenferink, A ;

Hunter, CN ;

Olsen, JD ;

Subramaniam, V ;

Otto, C .

JOURNAL OF MICROSCOPY, 2005, 217 :109-116

[66] Antibody-Unfolding and Metastable-State Binding in Force Spectroscopy and Recognition Imaging [J].

Kaur, Parminder ;

Qiang-Fu ;

Fuhrmann, Alexander ;

Ros, Robert ;

Kutner, Linda Obenauer ;

Schneeweis, Lumelle A. ;

Navoa, Ryman ;

Steger, Kirby ;

Xie, Lei ;

Yonan, Christopher ;

Abraham, Ralph ;

Grace, Michael J. ;

Lindsay, Stuart .

BIOPHYSICAL JOURNAL, 2011, 100 (01) :243-250

[67] Mass spectrometric detection of the amino acid sequence polymorphism of the hepatitis C virus antigen [J].

Kaysheva, A. L. ;

Ivanov, Yu. D. ;

Frantsuzov, P. A. ;

Krohin, N. V. ;

Pavlova, T. I. ;

Uchaikin, V. F. ;

Konev, V. A. ;

Kovalev, O. B. ;

Ziborov, V. S. ;

Archakov, A. I. .

JOURNAL OF VIROLOGICAL METHODS, 2016, 229 :86-90

[68] Visualization and identification of hepatitis C viral particles by atomic force microscopy combined with MS/MS analysis [J].

Kaysheva A.L. ;

Ivanov Y.D. ;

Zgoda V.G. ;

Frantsuzov P.A. ;

Pleshakova T.O. ;

Krokhin N.V. ;

Ziborov V.S. ;

Archakov A.I. .

Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 2010, 4 (1) :15-24

[69] Biospectroscopy of Nanodiamond-Induced Alterations in Conformation of Intra- and Extracellular Proteins: A Nanoscale IR Study [J].

Khanal, Dipesh ;

Kondyurin, Alexey ;

Hau, Herman ;

Knowles, Jonathan C. ;

Levinson, Olga ;

Ramzan, Iqbal ;

Fu, Dong ;

Marcott, Curtis ;

Chrzanowski, Wojciech .

ANALYTICAL CHEMISTRY, 2016, 88 (15) :7530-7538

[70] Molecular recognition imaging and force spectroscopy of single biomolecules [J].

Kienberger, F ;

Ebner, A ;

Gruber, HJ ;

Hinterdorfer, P .

ACCOUNTS OF CHEMICAL RESEARCH, 2006, 39 (01) :29-36

← 2 3 4 5 6 7 8 9 10 11 →