Liver diseases in the elderly

被引：2

作者：

Bruguera, Miguel ^{[1
,2
]}

机构：

[1] Hosp Clin Barcelona, Serv Hepatol, Barcelona, Spain

[2] Univ Barcelona, Dept Med, Barcelona, Spain

来源：

GASTROENTEROLOGIA Y HEPATOLOGIA | 2014年 / 37卷 / 09期

关键词：

Hepatitis; Cirrhosis; Alcoholic liver disease; Autoimmune hepatitis; HEPATITIS-C VIRUS; HEPATOCELLULAR-CARCINOMA; AUTOIMMUNE HEPATITIS; GENERAL-POPULATION; NATURAL-HISTORY; CLINICAL CHARACTERISTICS; VIRAL-HEPATITIS; OLDER PATIENTS; RISK-FACTORS; INFECTION;

D O I：

10.1016/j.gastrohep.2014.04.005

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Liver diseases in the elderly have aroused less interest than diseases of other organs, since the liver plays a limited role in aging. There are no specific liver diseases of old age, but age-related anatomical and functional modifications of the liver cause changes in the frequency and clinical behavior of some liver diseases compared with those in younger patients. This review discusses the most important features of liver function in the healthy elderly population, as well as the features of the most prevalent liver diseases in this age group, especially the diagnostic approach to the most common liver problems in the elderly: asymptomatic elevation of serum transaminases and jaundice. (C) 2014 Elsevier Espana, S.L.U. and AEEH y AEG. All rights reserved.

引用

页码：535 / 543

页数：9

共 66 条

[1] The natural history of nonalcoholic fatty liver disease: A population-based cohort study [J].

Adams, LA ;

Lymp, JF ;

St Sauver, J ;

Sanderson, SO ;

Lindor, KD ;

Feldstein, A ;

Angulo, P .

GASTROENTEROLOGY, 2005, 129 (01) :113-121

[2] Autoimmune hepatitis (AIH) in the elderly: A systematic retrospective analysis of a large group of consecutive patients with definite AM followed at a tertiary referral centre [J].

Al-Chalabi, Thawab ;

Boccato, Sylvia ;

Portmann, Bernard C. ;

McFarlane, Ian G. ;

Heneghan, Michael A. .

JOURNAL OF HEPATOLOGY, 2006, 45 (04) :575-583

[3] Wilson disease in septuagenarian siblings: Raising the bar for diagnosis [J].

Ala, A ;

Borjigin, J ;

Rochwarger, A ;

Schilsky, N .

HEPATOLOGY, 2005, 41 (03) :668-670

[4]

Angeli P, 1996, HEPATOLOGY, V23, P264

[5] Natural history of compensated viral cirrhosis:: a prospective study on the incidence and hierarchy of major complications [J].

Benvegnù, L ;

Gios, M ;

Boccato, S ;

Alberti, A .

GUT, 2004, 53 (05) :744-749

[6] Incidence, Presentation, and Outcomes in Patients With Drug-Induced Liver Injury in the General Population of Iceland [J].

Bjornsson, Einar S. ;

Bergmann, Ottar M. ;

Bjornsson, Helgi K. ;

Kvaran, Runar B. ;

Olafsson, Sigurdur .

GASTROENTEROLOGY, 2013, 144 (07) :1419-U168

[7]

Bruguera M, 1999, MED CLIN-BARCELONA, V112, P406

[8] Outbreak of nosocomial hepatitis C virus infection resolved by genetic analysis of HCV RNA [J].

Bruguera, M ;

Saiz, JC ;

Franco, S ;

Giménez-Barcons, M ;

Sánchez-Tapias, JM ;

Fabregas, S ;

Vega, R ;

Camps, N ;

Domínguez, A ;

Salleras, L .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (11) :4363-4366

[9] Cryptogenic cirrhosis: Clinical characterization and risk factors for underlying disease [J].

Caldwell, SH ;

Oelsner, DH ;

Iezzoni, JC ;

Hespenheide, EE ;

Battle, EH ;

Driscoll, CJ .

HEPATOLOGY, 1999, 29 (03) :664-669

[10] Long-term results of liver transplantation in patients 60 years of age and older [J].

Collins, BH ;

Pirsch, JD ;

Becker, YT ;

Hanaway, MJ ;

Van der Werf, WJ ;

D'Alessandro, AM ;

Knechtle, SJ ;

Odorico, JS ;

Leverson, G ;

Musat, A ;

Armbrust, M ;

Becker, BN ;

Sollinger, HW ;

Kalayoglu, M .

TRANSPLANTATION, 2000, 70 (05) :780-783

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