Practitioner's Guide to Latent Class Analysis: Methodological Considerations and Common Pitfalls

被引:535
作者
Sinha, Pratik [1 ,2 ]
Calfee, Carolyn S. [1 ,2 ]
Delucchi, Kevin L. [3 ]
机构
[1] Univ Calif San Francisco, Dept Med, Div Pulm Crit Care Allergy & Sleep Med, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Dept Psychiat, San Francisco, CA USA
关键词
clustering algorithms; data science; heterogeneity; latent class analysis; phenotypes; MODEL SELECTION; LUNG-FUNCTION; MONTE-CARLO; SUBPHENOTYPES; NUMBER; PERFORMANCE; VALIDATION; PHENOTYPES; COMPONENTS; ARDS;
D O I
10.1097/CCM.0000000000004710
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Latent class analysis is a probabilistic modeling algorithm that allows clustering of data and statistical inference. There has been a recent upsurge in the application of latent class analysis in the fields of critical care, respiratory medicine, and beyond. In this review, we present a brief overview of the principles behind latent class analysis. Furthermore, in a stepwise manner, we outline the key processes necessary to perform latent class analysis including some of the challenges and pitfalls faced at each of these steps. The review provides a one-stop shop for investigators seeking to apply latent class analysis to their data.
引用
收藏
页码:E63 / E79
页数:17
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