Effect of leptin gene polymorphisms on growth, slaughter and meat quality traits of grazing Brangus steers

被引：28

作者：

Corva, P. M. ^{[1
]}

Fernandez Macedo, G. V. ^{[1
]}

Soria, L. A. ^{[2
]}

Mazzucco, J. Papaleo ^{[3
]}

Motter, M. ^{[2
]}

Villarreal, E. L. ^{[3
]}

Schor, A. ^{[4
]}

Mezzadra, C. A. ^{[3
]}

Melucci, L. M. ^{[1
]}

Miquel, M. C. ^{[2
]}

机构：

[1] Univ Nacl Mar del Plata, Fac Ciencias Agr, Dept Anim Prod, Balcarce, Argentina

[2] Univ Buenos Aires, Fac Ciencias Vet, Area Genet, Buenos Aires, DF, Argentina

[3] Inst Nacl Tecnol Agropecuaria, Balcarce, Argentina

[4] Univ Buenos Aires, Fac Agron, Lab Carnes, Buenos Aires, DF, Argentina

来源：

GENETICS AND MOLECULAR RESEARCH | 2009年 / 8卷 / 01期

关键词：

Beef cattle; Brangus; Leptin; Body composition; Beef quality; SINGLE NUCLEOTIDE POLYMORPHISMS; BEEF-CATTLE; MISSENSE MUTATION; FEED-INTAKE; DAIRY-COWS; CARCASS; ASSOCIATION; PERFORMANCE; EXPRESSION; BEHAVIOR;

D O I：

10.4238/vol8-1gmr556

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Leptin is a hormone that affects the regulation of feed intake, energy balance and body composition in mammals. Several polymorphisms in the bovine leptin gene have been associated with phenotypic variance of these traits. We evaluated two known single nucleotide polymorphisms (SNPs) in the leptin gene of 253 grazing Brangus steers. Brangus is a 5/8 Angus-3/8 Brahman composite. Data were collected during two consecutive growth/fattening cycles from two farms in southeast Buenos Aires province, Argentina. One of the markers is in the promoter region of the gene (SNP1) and the other is a non-synonymous polymorphism in exon 2 (SNP2). The traits that we evaluated were live weight gain in the spring, gain in backfat thickness in the spring, final live weight, final ultrasound backfat thickness, final ultrasound rib eye area, carcass weight and length, carcass yield, kidney fat, kidney fat percentage, backfat thickness, rib eye area, and intramuscular fat percentage. Both markers affected some meat traits; though the only significant associations were of SNP1 with ultrasound rib eye area and of SNP2 with carcass yield and backfat thickness. Under the same conditions as in the present study, leptin markers could be of help only as part of a larger genotyping panel including other relevant genes.

引用

页码：105 / 116

页数：12

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