Anticoagulation Management in Geriatric Orthopedic Trauma Patients

被引:1
作者
Morris, Jensa C. [1 ]
O'Connor, Mary I. [2 ]
机构
[1] Yale New Haven Med Ctr, Hospitalist Serv, 20 York St, New Haven, CT 06510 USA
[2] Yale Univ, Dept Orthopaed & Rehabil, New Haven, CT USA
关键词
Geriatric; Anticoagulation; Hip fracture surgery; Trauma; Perioperative care; Atrial fibrillation; PROTHROMBIN COMPLEX CONCENTRATE; WARFARIN; GUIDELINES; SOCIETY;
D O I
10.1007/s13670-020-00345-3
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Purpose of Review This article will review the perioperative management of geriatric patients on anticoagulants who present for non-elective orthopedic surgery. Recent Findings Our understanding of best practices in perioperative anticoagulation management has advanced significantly over the last 5 years. More patients are presenting for surgery on direct oral anticoagulants which require a different approach than the vitamin K antagonist, warfarin. We have come to better appreciate the importance of time to the operating room on outcomes, specifically in hip fracture surgery. Regional anesthesia now has standardized guidelines for preprocedure anticoagulation interruption. Prothrombin complex concentrate has increasing acceptance for warfarin reversal preoperatively. Reversal agents are now available for the direct oral anticoagulants but are not recommended for standard use preprocedure. And there has been a shift away from routine use of bridging anticoagulation periprocedure. A team-based approach with input from the surgical, anesthesia, and internal medicine or geriatric team preoperatively is critical to the management of perioperative anticoagulation.
引用
收藏
页码:288 / 295
页数:8
相关论文
共 31 条
[1]   When patients on target-specific oral anticoagulants need surgery [J].
Anderson, Mary ;
Hassell, Kathryn L. ;
Trujillo, Toby C. ;
Wolfe, Brian .
CLEVELAND CLINIC JOURNAL OF MEDICINE, 2014, 81 (10) :629-639
[2]  
Ang D, 2017, AM SURGEON, V83, P527
[3]  
ASRA, 2018, ASRA COAGS 2 1
[4]   Prothrombin Complex Concentrates: An Alternative to Fresh Frozen Plasma [J].
Burk, David R. ;
Smith, Jordan L. ;
Wild, Jason R. .
ORTHOPEDICS, 2017, 40 (02) :E367-E369
[5]   Quality Improvement Guidelines for the Performance of Inferior Vena Cava Filter Placement for the Prevention of Pulmonary Embolism [J].
Caplin, Drew M. ;
Nikolic, Boris ;
Kalva, Sanjeeva P. ;
Ganguli, Suvranu ;
Saad, Wael E. A. ;
Zuckerman, Darryl A. .
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2011, 22 (11) :1499-1506
[6]   The impact of warfarin on operative delay and 1-year mortality in elderly patients with hip fracture: a retrospective observational study [J].
Caruso, Gaetano ;
Andreotti, Mattia ;
Marko, Tedi ;
Tonon, Francesco ;
Corradi, Nicola ;
Rizzato, Damiano ;
Valentini, Alessandra ;
Valpiani, Giorgia ;
Massari, Leo .
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH, 2019, 14 (1)
[7]   Dabigatran versus Warfarin in Patients with Atrial Fibrillation. [J].
Connolly, Stuart J. ;
Ezekowitz, Michael D. ;
Yusuf, Salim ;
Eikelboom, John ;
Oldgren, Jonas ;
Parekh, Amit ;
Pogue, Janice ;
Reilly, Paul A. ;
Themeles, Ellison ;
Varrone, Jeanne ;
Wang, Susan ;
Alings, Marco ;
Xavier, Denis ;
Zhu, Jun ;
Diaz, Rafael ;
Lewis, Basil S. ;
Darius, Harald ;
Diener, Hans-Christoph ;
Joyner, Campbell D. ;
Wallentin, Lars .
NEW ENGLAND JOURNAL OF MEDICINE, 2009, 361 (12) :1139-1151
[8]   Prevalence and Implications of Preinjury Warfarin Use An Analysis of the National Trauma Databank [J].
Dossett, Lesly A. ;
Riesel, Johanna N. ;
Griffin, Marie R. ;
Cotton, Bryan A. .
ARCHIVES OF SURGERY, 2011, 146 (05) :565-570
[9]   Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation [J].
Douketis, James D. ;
Spyropoulos, Alex C. ;
Kaatz, Scott ;
Becker, Richard C. ;
Caprini, Joseph A. ;
Dunn, Andrew S. ;
Garcia, David A. ;
Jacobson, Alan ;
Jaffer, Amir K. ;
Kong, David F. ;
Schulman, Sam ;
Turpie, Alexander G. G. ;
Hasselblad, Vic ;
Ortel, Thomas L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 373 (09) :823-833
[10]   Perioperative Management of Antithrombotic Therapy Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence- Based Clinical Practice Guidelines [J].
Douketis, James D. ;
Spyropoulos, Alex C. ;
Spencer, Frederick A. ;
Mayr, Michael ;
Jaffer, Amir K. ;
Eckman, Mark H. ;
Dunn, Andrew S. ;
Kunz, Regina .
CHEST, 2012, 141 (02) :E326S-E350S