Temperature-Responsive Cell Culture Surface for Cell-Sheet Tissue Engineering and Its Design to Express Temperature-Dependent Cell Attachment/Detachment Character

被引：2
作者：
Akiyama, Yoshikatsu [1 ]
Okano, Teruo [1 ]
机构：
[1] Tokyo Womens Med Univ, Inst Adv Biomed Engn & Sci, Shinjuku Ku, 8-1 Kawadacho, Tokyo 1628666, Japan
来源：
KOBUNSHI RONBUNSHU | 2018年 / 75卷 / 02期
关键词：
Poly(N-isopropylacrylamide); Intelligent Interface; Temeprature-Responsive Cell Culture Surface; Cell-Sheet; Tissue Engineering; THERMORESPONSIVE POLYMER BRUSHES; N-ISOPROPYLACRYLAMIDE; POLY(N-ISOPROPYLACRYLAMIDE)-GRAFTED SURFACES; 2-DIMENSIONAL MANIPULATION; PERIODONTAL REGENERATION; EXTRACELLULAR-MATRIX; ENDOTHELIAL-CELLS; HARVESTING CELLS; DRUG-RELEASE; DETACHMENT;
D O I：
10.1295/koron.2017-0078
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
In this review, we focus on the progress of temperature-responsive cell culture surface (TRCS), which is a poly(N-isopropylacrylamide) (PIPAAm) grafted surface, since the first report of temperature-responsive surfaces. We also show that the optimization of the grafted nano-scaled PIPAAm layer is essential to express temperature dependent cell attachment/detachment. Also, we describe the technologies required to readily fabricate cell sheets and TRCS in the near future, which are quantitative methods for cell adhesion/detachment processes from TRCS by using micro fluidic technique and a facile method for preparation of TRCS.
引用
收藏
页码：174 / 186
页数：13
相关论文
共 92 条
[1]   Ultrathin poly(N-isopropylacrylamide) grafted layer on polystyrene surfaces for cell adhesion/detachment control [J].
Akiyama, Y ;
Kikuchi, A ;
Yamato, M ;
Okano, T .
LANGMUIR, 2004, 20 (13) :5506-5511
[2]   Surface characterization of poly(N-isopropylacrylamide) grafted tissue culture polystyrene by electron beam irradiation, using atomic force microscopy, and X-ray photoelectron spectroscopy [J].
Akiyama, Yoshikatsu ;
Kushida, Ai ;
Yamato, Masayuki ;
Kikuchi, Akihiko ;
Okano, Teruo .
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2007, 7 (03) :796-802
[3]   Accelerated cell-sheet recovery from a surface successively grafted with polyacrylamide and poly(N-isopropylacrylamide) [J].
Akiyama, Yoshikatsu ;
Kikuchi, Akihiko ;
Yamato, Masayuki ;
Okano, Teruo .
ACTA BIOMATERIALIA, 2014, 10 (08) :3398-3408
[4]   One-component bimolecular photoinitiating systems, 2 - Thioxanthone acetic acid derivatives as photoinitiators for free radical polymerization [J].
Aydin, M ;
Arsu, N ;
Yagci, Y .
MACROMOLECULAR RAPID COMMUNICATIONS, 2003, 24 (12) :718-723
[5]  
Biazar E, 2010, INT J NANOMED, V5, P549
[6]   Neural cell pattern formation on glass and oxidized silicon surfaces modified with poly(N-isopropylacrylamide) [J].
Bohanon, T ;
Elender, G ;
Knoll, W ;
Koberle, P ;
Lee, JS ;
Offenhausser, A ;
Ringsdorf, H ;
Sackmann, E ;
Simon, J ;
Tovar, G ;
Winnik, FM .
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 1996, 8 (01) :19-39
[7]   Cell sheet detachment affects the extracellular matrix: A surface science study comparing thermal liftoff, enzymatic, and mechanical methods [J].
Canavan, HE ;
Cheng, XH ;
Graham, DJ ;
Ratner, BD ;
Castner, DG .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2005, 75A (01) :1-13
[8]  
Chen GP, 1998, J BIOMED MATER RES, V42, P38, DOI 10.1002/(SICI)1097-4636(199810)42:1<38::AID-JBM6>3.0.CO
[9]  
2-P
[10]   Surface chemical and mechanical properties of plasma-polymerized N-isopropylacrylamide [J].
Cheng, XH ;
Canavan, HE ;
Stein, MJ ;
Hull, JR ;
Kweskin, SJ ;
Wagner, MS ;
Somorjai, GA ;
Castner, DG ;
Ratner, BD .
LANGMUIR, 2005, 21 (17) :7833-7841
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