Putting a brake on an autonomous DNA nanomotor

被引：72

作者：

Chen, Y ^{[1
]}

Mao, CD ^{[1
]}

机构：

[1] Purdue Univ, Dept Chem, W Lafayette, IN 47906 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 28期

关键词：

D O I：

10.1021/ja047991r

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A strategy was developed to reversibly switch on/off an autonomous DNA nanomotor that contains a DNA enzyme. The multiple RNA cleavage of the DNAzyme powered the motor to move, and a strand displacement mechanism provided the basis for a reversible brake to the motor. Copyright © 2004 American Chemical Society.

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收藏

页码：8626 / 8627

页数：2

相关论文

共 27 条

[1] MOLECULAR COMPUTATION OF SOLUTIONS TO COMBINATORIAL PROBLEMS [J].

ADLEMAN, LM .

SCIENCE, 1994, 266 (5187) :1021-1024

[2] DNA duplex-quadruplex exchange as the basis for a nanomolecular machine [J].

Alberti, P ;

Mergny, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (04) :1569-1573

[3] Photoinduction of fast, reversible translational motion in a hydrogen-bonded molecular shuttle [J].

Brouwer, AM ;

Frochot, C ;

Gatti, FG ;

Leigh, DA ;

Mottier, L ;

Paolucci, F ;

Roffia, S ;

Wurpel, GWH .

SCIENCE, 2001, 291 (5511) :2124-2128

[4]

CHEN Y, 2004, IN PRESS ANGEW CHEM

[5] A [2]catenane-based solid state electronically reconfigurable switch [J].

Collier, CP ;

Mattersteig, G ;

Wong, EW ;

Luo, Y ;

Beverly, K ;

Sampaio, J ;

Raymo, FM ;

Stoddart, JF ;

Heath, JR .

SCIENCE, 2000, 289 (5482) :1172-1175

[6] Nanoelectromechanical systems [J].

Craighead, HG .

SCIENCE, 2000, 290 (5496) :1532-1535

[7] A two-state DNA lattice switched by DNA nanoactuator [J].

Feng, LP ;

Park, SH ;

Reif, JH ;

Yan, H .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (36) :4342-4346

[8] Determination of DNA helical handedness by fluorescence resonance energy transfer [J].

JaresErijman, EA ;

Jovin, TM .

JOURNAL OF MOLECULAR BIOLOGY, 1996, 257 (03) :597-617

[9] Light-driven monodirectional molecular rotor [J].

Koumura N. ;

Zijistra R.W.J. ;

Van Delden R.A. ;

Harada N. ;

Feringa B.L. .

Nature, 1999, 401 (6749) :152-155

[10] Unidirectional rotation in a mechanically interlocked molecular rotor [J].

Leigh, DA ;

Wong, JKY ;

Dehez, F ;

Zerbetto, F .

NATURE, 2003, 424 (6945) :174-179