Sonogashira coupling reactions of highly oxygenated vinyl halides: The first synthesis of harveynone and epi-harveynone

被引:63
作者
Graham, AE
McKerrecher, D
Davies, DH
Taylor, RJK
机构
[1] UNIV YORK,DEPT CHEM,YORK YO1 5DD,N YORKSHIRE,ENGLAND
[2] ZENECA PHARMACEUT,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND
关键词
D O I
10.1016/0040-4039(96)01607-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Sonogashira coupling reactions of highly functionalised cyctohexenyl halides have been developed and utilised to prepare the naturally-occurring anti-cancer agent harveynone and its C-4 epimer. Copyright (C) 1996 Elsevier Science Ltd
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页码:7445 / 7448
页数:4
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