Approaches to the treatment of disease induced by chikungunya virus

被引：0
|
作者：
Bettadapura, Jayaram [1 ]
Herrero, Lara J. [1 ]
Taylor, Adam [1 ]
Mahalingam, Suresh [1 ]
机构：
[1] Griffith Univ, Inst Glyc, Emerging Viruses & Inflammat Res Grp, Nathan, Qld 4222, Australia
来源：
INDIAN JOURNAL OF MEDICAL RESEARCH | 2013年 / 138卷
基金：
英国医学研究理事会;
关键词：
Antivirals; arthralgia; chikungunya; CHIKV; vaccines; MOUSE MODEL; ANTIVIRAL ACTIVITY; VACCINE; ARTHRITIS; REPLICATION; INHIBITION; INFECTION; IMMUNOGENICITY; IDENTIFICATION; EPIDEMIC;
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Chikungunya virus, a re-emerging mosquito-borne alphavirus, causes fever, rash and persistent arthralgia/arthritis in humans. Severe outbreaks have occurred resulting in infections of millions of people in Southeast Asia and Africa. Currently there are no antiviral drugs or vaccines for prevention and treatment of chikungunya infections. Herein we report the current status of research on antiviral drugs and vaccines for chikungunya virus infections.
引用
收藏
页码：762 / 765
页数：4
相关论文
共 50 条
  • [31] Fingolimod treatment abrogates chikungunya virus-induced arthralgia
    Teo, Teck-Hui
    Chan, Yi-Hao
    Lee, Wendy W. L.
    Lum, Fok-Moon
    Amrun, Siti Naqiah
    Her, Zhisheng
    Rajarethinam, Ravisankar
    Merits, Andres
    Rotzschke, Olaf
    Renia, Laurent
    Ng, Lisa F. P.
    SCIENCE TRANSLATIONAL MEDICINE, 2017, 9 (375)
  • [32] Chikungunya virus replication in skeletal muscle cells is required for disease development
    Lentscher, Anthony J.
    McCarthy, Mary K.
    May, Nicholas A.
    Davenport, Bennett J.
    Montgomery, Stephanie A.
    Raghunathan, Krishnan
    McAllister, Nicole
    Silva, Laurie A.
    Morrison, Thomas E.
    Dermody, Terence S.
    JOURNAL OF CLINICAL INVESTIGATION, 2020, 130 (03) : 1466 - 1478
  • [33] Animal Models of Chikungunya Virus Infection and Disease
    Haese, Nicole N.
    Broeckel, Rebecca M.
    Hawman, David W.
    Heise, Mark T.
    Morrison, Thomas E.
    Streblow, Daniel N.
    JOURNAL OF INFECTIOUS DISEASES, 2016, 214 : S482 - S487
  • [34] Expression profile of immune response genes during acute myopathy induced by chikungunya virus in a mouse model
    Patil, Dilip R.
    Hundekar, Supriya L.
    Arankalle, Vidya A.
    MICROBES AND INFECTION, 2012, 14 (05) : 457 - 469
  • [35] Mosquito saliva induced cutaneous events augment Chikungunya virus replication and disease progression
    Agarwal, Ankita
    Joshi, Gaurav
    Nagar, Durga P.
    Sharma, Ajay K.
    Sukumaran, D.
    Pant, Satish C.
    Parida, Man Mohan
    Dasha, Paban Kumar
    INFECTION GENETICS AND EVOLUTION, 2016, 40 : 126 - 135
  • [36] Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques
    Broeckel, Rebecca
    Fox, Julie M.
    Haese, Nicole
    Kreklywich, Craig N.
    Sukulpovi-Petty, Soila
    Legasse, Alfred
    Smith, Patricia P.
    Denton, Michael
    Corvey, Carsten
    Krishnan, Shiv
    Colgin, Lois M. A.
    Ducore, Rebecca M.
    Lewis, Anne D.
    Axthelm, Michael K.
    Mandron, Marie
    Cortez, Pierre
    Rothblatt, Jonathan
    Rao, Ercole
    Focken, Ingo
    Carter, Kara
    Sapparapau, Gopal
    Crowe, James E., Jr.
    Diamond, Michael S.
    Streblow, Daniel N.
    PLOS NEGLECTED TROPICAL DISEASES, 2017, 11 (06):
  • [37] New Approaches to Chikungunya Virus Vaccine Development
    Garcia, Alexis
    Diego, Lema
    Judith, Barroso
    RECENT PATENTS ON INFLAMMATION & ALLERGY DRUG DISCOVERY, 2015, 9 (01) : 31 - 37
  • [38] Emergence and clinical insights into the pathology of Chikungunya virus infection
    Jaffar-Bandjee, Marie Christine
    Ramful, Duksha
    Gauzere, Bernard Alex
    Hoarau, Jean Jacques
    Krejbich-Trotot, Pascale
    Robin, Stephanie
    Ribera, Anne
    Selambarom, Jimmy
    Gasque, Philippe
    EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 2010, 8 (09) : 987 - 996
  • [39] Arthralgia resolution rate following chikungunya virus infection
    O'Driscoll, Megan
    Salje, Henrik
    Chang, Aileen Y.
    Watson, Hugh
    INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2021, 112 : 1 - 7
  • [40] Development and Application of Treatment for Chikungunya Fever
    Millsapps, Erin M.
    Underwood, Emma C.
    Barr, Kelli L.
    RESEARCH AND REPORTS IN TROPICAL MEDICINE, 2022, 13 : 55 - 66
12345