Approaches to the treatment of disease induced by chikungunya virus

被引:0
|
作者
Bettadapura, Jayaram [1 ]
Herrero, Lara J. [1 ]
Taylor, Adam [1 ]
Mahalingam, Suresh [1 ]
机构
[1] Griffith Univ, Inst Glyc, Emerging Viruses & Inflammat Res Grp, Nathan, Qld 4222, Australia
基金
英国医学研究理事会;
关键词
Antivirals; arthralgia; chikungunya; CHIKV; vaccines; MOUSE MODEL; ANTIVIRAL ACTIVITY; VACCINE; ARTHRITIS; REPLICATION; INHIBITION; INFECTION; IMMUNOGENICITY; IDENTIFICATION; EPIDEMIC;
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Chikungunya virus, a re-emerging mosquito-borne alphavirus, causes fever, rash and persistent arthralgia/arthritis in humans. Severe outbreaks have occurred resulting in infections of millions of people in Southeast Asia and Africa. Currently there are no antiviral drugs or vaccines for prevention and treatment of chikungunya infections. Herein we report the current status of research on antiviral drugs and vaccines for chikungunya virus infections.
引用
收藏
页码:762 / 765
页数:4
相关论文
共 50 条
  • [21] Molecular epidemiology, evolution and phylogeny of Chikungunya virus: An updating review
    Lo Presti, Alessandra
    Cella, Eleonora
    Angeletti, Silvia
    Ciccozzi, Massimo
    INFECTION GENETICS AND EVOLUTION, 2016, 41 : 270 - 278
  • [22] Therapeutics and Vaccines Against Chikungunya Virus
    Ahola, Tero
    Courderc, Therese
    Ng, Lisa F. P.
    Hallengard, David
    Powers, Ann
    Lecuit, Marc
    Esteban, Mariano
    Merits, Andres
    Roques, Pierre
    Liljestrom, Peter
    VECTOR-BORNE AND ZOONOTIC DISEASES, 2015, 15 (04) : 250 - 257
  • [23] RNAi agents as chikungunya virus therapeutics
    Parashar, Deepti
    Cherian, Sarah
    FUTURE VIROLOGY, 2016, 11 (05) : 321 - 329
  • [24] Chikungunya Virus-Associated Disease
    Hua, C.
    Combe, B.
    CURRENT RHEUMATOLOGY REPORTS, 2017, 19 (11)
  • [25] Next generation sequencing of DNA-launched Chikungunya vaccine virus
    Hidajat, Rachmat
    Nickols, Brian
    Forrester, Naomi
    Tretyakova, Irina
    Weaver, Scott
    Pushko, Peter
    VIROLOGY, 2016, 490 : 83 - 90
  • [26] Paradoxical Effect of Chloroquine Treatment in Enhancing Chikungunya Virus Infection
    Roques, Pierre
    Thiberville, Simon-Djamel
    Dupuis-Maguiraga, Laurence
    Lum, Fok-Moon
    Labadie, Karine
    Martinon, Frederic
    Gras, Gabriel
    Lebon, Pierre
    Ng, Lisa F. P.
    de Lamballerie, Xavier
    Le Grand, Roger
    VIRUSES-BASEL, 2018, 10 (05):
  • [27] Defining a correlate of protection for chikungunya virus vaccines
    Milligan, Gregg N.
    Schnierle, Barbara S.
    McAuley, Alexander J.
    Beasley, David W. C.
    VACCINE, 2019, 37 (50) : 7427 - 7436
  • [28] In silico studies of fisetin and silymarin as novel chikungunya virus nonstructural proteins inhibitors
    Lani, Rafidah
    Agharbaoui, Fatima Ezzahra
    Hassandarvish, Pouya
    Teoh, Boon Teong
    Sam, Sing Sin
    Zandi, Keivan
    Rahman, Noorsaadah Abd
    AbuBakar, Sazaly
    FUTURE VIROLOGY, 2021, 16 (03) : 167 - 180
  • [29] Stimulation of dendritic cell functional maturation by capsid protein from chikungunya virus
    Vu Xuan Nghia
    Nguyen Van Giang
    Nguyen Xuan Canh
    Nguyen Hai Ha
    Nguyen Thuy Duong
    Nguyen Huy Hoang
    Nguyen Thi Xuan
    IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2020, 23 (10) : 1268 - 1274
  • [30] Targeting Chikungunya virus by computational approaches: from viral biology to the development of therapeutic strategies
    Rabelo, Vitor Won-Held
    Nunes de Palmer Paixao, Izabel Christina
    Abreu, Paula Alvarez
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2020, 24 (01) : 63 - 78