Effects of mindfulness and psychoeducation on working memory in adult ADHD: A randomised, controlled fMRI study

被引：47

作者：

Bachmann, Katharina ^{[1
]}

Lam, Alexandra P. ^{[1
,2
]}

Soeroes, Peter ^{[1
,3
]}

Kanat, Manuela ^{[4
]}

Hoxhaj, Eliza ^{[5
]}

Matthies, Swantje ^{[5
]}

Feige, Bernd ^{[5
]}

Mueller, Helge ^{[1
]}

Oezyurt, Jale ^{[2
,3
]}

Thiel, Christiane M. ^{[2
,3
]}

Philipsen, Alexandra ^{[1
,5
,6
]}

机构：

[1] Med Campus Univ Oldenburg, Sch Med & Hlth Sci Psychiat & Psychotherapy, Univ Hosp, Karl Jaspers Klin, Hermann Ehlers Str 7, D-26160 Bad Zwischenahn, Germany

[2] Carl von Ossietzky Univ Oldenburg, European Med Sch, Dept Psychol, Biol Psychol Lab, Oldenburg, Germany

[3] Carl von Ossietzky Univ Oldenburg, Res Ctr Neurosensory Sci, Oldenburg, Germany

[4] Univ Freiburg, Sect Hlth Care Res & Rehabil Res, Inst Med Biometry & Stat, Med Ctr,Fac Med, Freiburg, Germany

[5] Univ Freiburg, Fac Med, Med Ctr, Dept Psychiat & Psychotherapy, Freiburg, Germany

[6] Univ Bonn, Dept Psychiat & Psychotherapy, Bonn, Germany

来源：

BEHAVIOUR RESEARCH AND THERAPY | 2018年 / 106卷

关键词：

Mindfulness; fMRI; ADHD; Adult; Neuropsychotherapy; Psychoeducation; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; MEDITATION; INTERVENTIONS; METAANALYSIS; NETWORK;

D O I：

10.1016/j.brat.2018.05.002

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Adult attention-deficit/hyperactivity disorder (ADHD) is a serious mental disorder associated with impaired neurocognitive performance related to working memory function. Recent clinical trials have suggested that mindfulness is a promising intervention in adults with ADHD. We performed a randomised controlled clinical trial to investigate working memory (WM) with an n-back task in adults with ADHD during fMRI before and after an 8-week mindfulness intervention (MAP) compared with psychoeducation (PE). ADHD symptoms were assessed using the self- and observer-rated Conners Adult ADHD Rating Scales (CAARS). The complete pre-post data of 21 MAP and 19 PE participants were analysed. We found no group difference in ADHD symptoms or task performance at the pre-measurement, but there was a significant decrease in ADHD symptoms and significant improvement in task performance in both groups at the post-measurement. Furthermore, we found a significant increase in task-related activation in the right parietal lobe, with no difference between groups. Exploratory two-sample paired t-tests revealed significant increased brain activation after MAP in the bilateral inferior parietal lobule, right posterior insula and right precuneus. A decrease in self rated 'Inattention/Memory Problems' after MAP compared to baseline was associated with stronger activation in parts of the left putamen, globus pallidus and thalamus.

引用

页码：47 / 56

页数：10

共 50 条

[1] Attention-Deficit/Hyperactivity Disorder (ADHD) and Working Memory in Adults: A Meta-Analytic Review [J].