Differential Analysis of Retinal Guanylyl Cyclase GUCY2D (RetGC1) Activation and Binding with GCAP1 and RD3 Using In Vitro Activity Assay and Cell-based Binding Assay

被引：0

作者：

Peshenko, Igor ^{[1
,2
]}

Olshevskaya, Elena ^{[1
,2
]}

Dizhoor, Alexander ^{[1
,2
]}

机构：

[1] Salus Univ, Penn Coll Optometry, Elkins Pk, PA USA

[2] Salus Univ, Dept Basic Sci, Elkins Pk, PA USA

来源：

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2013年 / 54卷 / 15期

关键词：

659 protein structure/function; 439; calcium; 648; photoreceptors;

D O I：

暂无

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

704

引用

页数：2

共 6 条

[1] Study of surface-exposed residues in retinal degeneration 3 (RD3) protein in regulation of retinal guanylyl cyclase RetGC1 (GUCY2D)
Peshenko, Igor
Dizhoor, Alexander M.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2020, 61 (07)
[2] Activation of Retinal Guanylyl Cyclase RetGC1 by GCAP1: Stoichiometry of Binding and Effect of New LCA-Related Mutations
Peshenko, Igor V.
Olshevskaya, Elena V.
Yao, Suxia
Ezzeldin, Hany H.
Pittler, Steven J.
Dizhoor, Alexander M.
BIOCHEMISTRY, 2010, 49 (04) : 709 - 717
[3] Binding of guanylyl cyclase activating protein 1 (GCAP1) to retinal guanylyl cyclase (RetGC1) - The role of individual EF-hands
Peshenko, Igor V.
Olshevskaya, Elena V.
Dizhoor, Alexander M.
JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (31) : 21747 - 21757
[4] Point mutations in guanylyl cyclase RetGC1 dimerization domain disrupt binding of GCAP1 and GCAP2.
Peshenko, Igor V.
Olshevskaya, Elena V.
Dizhoor, Alexander M.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2015, 56 (07)
[5] Mutually exclusive binding of guanylyl cyclase activating proteins (GCAP) to retinal guanylyl cyclase 1 (RetGC1): implications for regulation of photoresponse and GUCY2D-linked Leber's congenital amaurosis.
Dizhoor, Alexander M.
Olshevskaya, Elena V.
Peshenko, Igor V.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2015, 56 (07)
[6] Mutation in human retinal membrane guanylyl cyclase 1 (RetGC1, GUCY2D) associated with CORD6 deregulates cGMP synthesis in photoreceptors and causes progressive blindness in transgenic mouse model.
Dizhoor, Alexander M.
Olshevskaya, Elena V.
Peshenko, Igor V.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (12)

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