The effect of metal-doped TiO2 nanoparticles on zebrafish embryogenesis

被引：19
作者：
Park, Hyung-Geun [1 ,2 ]
Kim, Jung In [1 ,2 ]
Kang, Misook [3 ]
Yeo, Min-Kyeong [1 ,2 ]
机构：
[1] Kyung Hee Univ, Coll Engn, Dept Environm Sci, Yongin 446701, Gyeonggi Do, South Korea
[2] Kyung Hee Univ, Coll Engn, Environm Res Ctr, Yongin 446701, Gyeonggi Do, South Korea
[3] Yeungnam Univ, Coll Sci, Dept Chem, Kyongsan 712749, Gyeongbuk, South Korea
来源：
MOLECULAR & CELLULAR TOXICOLOGY | 2014年 / 10卷 / 03期
基金：
新加坡国家研究基金会;
关键词：
Metal-doped TiO2 nanoparticles; Photocatalysis; Energy efficiency; Toxicity; Zebrafish embryos; HYDROGEN-PRODUCTION; OXIDATIVE STRESS; TOXICITY; DEGRADATION; PHOTOCATALYST; PERFORMANCE; MECHANISM; EXPOSURE; NANO; ZNO;
D O I：
10.1007/s13273-014-0033-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this study, we manufactured metal-doped TiO2 nanoparticles using several transition metals (Mn, Fe, Ni, and Cu). Their physicochemical properties were evaluated by transmission electron microscopy (TEM), X-ray diffiaction (XRD) analysis, and UV-visible spectra. The energy efficiency of the metals increased in the order of Ni- < Cu- < Mn- < Fe-TiO2. For toxicity testing, zebrafish embryos were exposed to 4 mg L-1 of metal-doped TiO2 nanoparticles. We determined the survival rate (%) and abnormal morphology rate (%) of the exposed embryos and also observed apoptosis and necrosis using confocal microscopy. The metal TiO2 nanoparticles showed acute toxicity in the order of Mn- < Cu- < Ni- <= Fe-TiO2. Although the Fe-TiO2 NPs group demonstrated the highest photocatalytic performance, it also exhibited the highest toxic effects. Among the metals, the Mn-TiO2 NPs group demonstrated improved photocatalysis compared to the other samples except for the Fe-TiO2 NPs along with the lowest toxic effects. For these reasons, the most suitable doping metal was the Mn-TiO2 NPs group considering its energy activity and environmental impacts.
引用
收藏
页码：293 / 301
页数：9
相关论文
共 35 条
[1]  
Aboelzahab A., 2012, INT SCH RES NOTICES, V2012, P1
[2]   Photocatalytic degradation of acetone, acetaldehyde and toluene in gas-phase: Comparison between nano and micro-sized TiO2 [J].
Bianchi, C. L. ;
Gatto, S. ;
Pirola, C. ;
Naldoni, A. ;
Di Michele, A. ;
Cerrato, G. ;
Crocella, V. ;
Capucci, V. .
APPLIED CATALYSIS B-ENVIRONMENTAL, 2014, 146 :123-130
[3]  
Chae J, 2009, B KOREAN CHEM SOC, V30, P302
[4]   Semiconductor-based Photocatalytic Hydrogen Generation [J].
Chen, Xiaobo ;
Shen, Shaohua ;
Guo, Liejin ;
Mao, Samuel S. .
CHEMICAL REVIEWS, 2010, 110 (11) :6503-6570
[5]   Enhanced photoelectrocatalytic performance for degradation of diclofenac and mechanism with TiO2 nano-particles decorated TiO2 nano-tubes arrays photoelectrode [J].
Cheng, Xiuwen ;
Liu, Huiling ;
Chen, Qinghua ;
Li, Junjing ;
Wang, Pu .
ELECTROCHIMICA ACTA, 2013, 108 :203-210
[6]   Determination of the mechanism of photoinduced toxicity of selected metal oxide nanoparticles (ZnO, CuO, Co3O4 and TiO2) to E-coli bacteria [J].
Dasari, Thabitha P. ;
Pathakoti, Kavitha ;
Hwang, Huey-Min .
JOURNAL OF ENVIRONMENTAL SCIENCES, 2013, 25 (05) :882-888
[7]   Evaluation of a continuous quantification method of apoptosis and necrosis in tissue cultures [J].
Gawlitta, D ;
Oomens, CWJ ;
Baaijens, FPT ;
Bouten, CVC .
CYTOTECHNOLOGY, 2004, 46 (2-3) :139-150
[8]   Transition metal ions effect on the properties and photocatalytic activity of nanocrystalline TiO2 prepared in an ionic liquid [J].
Ghasemi, S. ;
Rahimnejad, S. ;
Setayesh, S. Rahman ;
Rohani, S. ;
Gholami, M. R. .
JOURNAL OF HAZARDOUS MATERIALS, 2009, 172 (2-3) :1573-1578
[9]   Effect of sub-acute exposure to TiO2 nanoparticles on oxidative stress and histopathological changes in Juvenile Carp (Cyprinus carpio) [J].
Hao Linhua ;
Wang Zhenyu ;
Xing Baoshan .
JOURNAL OF ENVIRONMENTAL SCIENCES, 2009, 21 (10) :1459-1466
[10]   Solvothermal synthesis of mesoporous TiO2: The effect of morphology, size and calcination progress on photocatalytic activity in the degradation of gaseous benzene [J].
He, Fei ;
Li, Jinlin ;
Li, Tao ;
Li, Guangxing .
CHEMICAL ENGINEERING JOURNAL, 2014, 237 :312-321
1234