Intranuclear Pseudo-inclusions and Grooves in Fine Needle Aspiration Cytology of Pulmonary Carcinoid Tumor

Cytologic findings of pulmonary carcinoid have been well described. Vile report new ologica findings in a case of carcinoid tumor. The patient is a 36-year-old man presenting with hemoptysis of about six months in duration. Chest CT scans showed a well-defined round polypoid lesion measuring 1 x 1 cm within the right upper lobe of the bronchus with hyperinflation of the right upper lobe. T rans-bronchial fine needle aspiration and biopsy were done. CYtologio smears showed isolated and loose clusters of uniform round to spindle shape cells with round centrally located nuclei, fine grantilar (salt and pepper) chromatin and pale cytoplasm. Intranuclear pseudo -inclusions and grooves were seen in some tumor cells. No nlitotio figures or necrosis were evident. A cytological diagnosis of carcinoid tumor was made and histopathologic examination and subsequent imrnunohistochemical study confirmed the diagriosis. Carcinoid tumi-.ir may be reliably diagriosed on fine needle aspiration cytology srriears. Intranuclear psetAdo-inclusioris arid grooves may be evident in tumor cells.