Two New Natural Products from Portulaca oleracea L. and their Antioxidant and Antiacetylcholinesterase Activities

被引：0

作者：

Xu, Haoran ^{[1
]}

Zhang, Wenjie ^{[1
]}

Leng, Aijing ^{[2
]}

Ying, Xixiang ^{[1
]}

机构：

[1] Liaoning Univ Tradit Chinese Med, Sch Pharm, Dalian, Peoples R China

[2] Dalian Med Univ, Affiliated Hosp 1, Dept Pharm, Dalian, Peoples R China

来源：

LATIN AMERICAN JOURNAL OF PHARMACY | 2018年 / 37卷 / 03期

基金：

中国国家自然科学基金;

关键词：

antiacetylcholinesterase activity; antioxidant activity; Portulaca oleracea L; two new natural products; ALZHEIMERS-DISEASE; ALKALOIDS; INHIBITORS; PLANTS;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Two new natural products already known from synthesis, benzoic acid, 4-[[(2-hydroxyethyl)amino]carbonyl]-methyl ester (1) and benzoic acid, 3-[[(2-hydroxyethyl)amino]carbonyl]-methyl ester (2) were isolated from Portulaca oleracea L. for the first time and their structures were identified using spectroscopic methods including (HNMR)-H-1, (CNMR)-C-13 and HR-ESI(+)-TOF-MS. Both compounds presented antioxidant activity with IC50 of 56.49 and 54.89 mu g/mL and antiacetylcholinesterase activitywith IC50 of 28.95 and 24.38 mu g/mL, respectively.

引用

页码：480 / 483

页数：4

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