qBrain-2, a POU domain gene expressed in quail embryos

被引：8
作者：
Liu, Y
Xue, JX
Zhang, W
Fu, DC
He, RQ
Xue, ZG
机构：
[1] Chinese Acad Sci, Inst Biophys, Lab Visual Informat Proc, Beijing 100101, Peoples R China
[2] Univ Paris 06, CNRS, URA 2115, F-75634 Paris 13, France
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 2000年 / 1491卷 / 1-3期
关键词：
qBrain-2; class III of POU domain gene; quail; central nervous system; in situ hybridization;
D O I：
10.1016/S0167-4781(00)00011-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We isolated a quail class III POU domain gene, qBrain-2, which was cloned from a cDNA library of E5 embryos. Northern blot and in situ hybridization analyses showed that qBrain-2 was expressed in developing central nervous system and adult brain. Moreover, qBrain-2 transcripts showed a dynamic distribution in embryonic central nervous system. Its transcripts were dominantly detected in the ventricular zone of the developing brain and spinal cord, but rarely in the differentiated region of mantle zone as well as the non-neuronal roof plate and floor plate. This suggests that qBrain-2 is involved in proliferation and differentiation of the neuroepithelial cells of quail central nervous system. (C) 2000 Elsevier Science B.V. All rights reserved.
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页码：27 / 36
页数：10
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