Molecular epidemiology of foot-and-mouth disease viruses from South East Asia 1998-2006: The Lao perspective

被引:23
作者
Khounsy, Syseng [2 ]
Conlan, James V. [1 ]
Gleeson, Laurence J. [1 ]
Westbury, Harvey A. [1 ]
Colling, Axel [1 ]
Paton, David J. [3 ]
Ferris, Nigel P. [3 ]
Valarcher, Jean-Francois [3 ,4 ]
Wadsworth, Jemma [3 ]
Knowles, Nick J. [3 ]
Blacksell, Stuart D. [5 ,6 ]
机构
[1] CSIRO Livestock Ind, Australian Anim Hlth Lab, Geelong, Vic 3220, Australia
[2] Minist Agr & Forestry, Dept Livestock & Fisheries, Lao Pdr, Australia
[3] AFRC, Inst Anim Hlth, Pirbright Lab, Woking GU24 0NF, Surrey, England
[4] Swedish Univ Agr Sci, Dept Clin Sci, SE-75007 Uppsala, Sweden
[5] Mahidol Univ, Fac Trop Med, Mahidol Oxford Trop Med Res Unit, Bangkok 10400, Thailand
[6] John Radcliffe Hosp, Nuffield Dept Clin Med, Ctr Trop Med, Oxford OX3 9DU, England
基金
英国生物技术与生命科学研究理事会;
关键词
Foot-and-mouth disease virus; Molecular epidemiology; VP1; Asia; Lao PDR; IMPACT;
D O I
10.1016/j.vetmic.2008.12.008
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Foot-and-mouth disease (FMD) causes sporadic disease outbreaks in the Lao People's Democratic Republic (Lao PDR) and appears to be endemic within a livestock population largely susceptible to infection. As Lao PDR is a major thoroughfare for transboundary animal movement, regular FMD outbreaks occur causing economic hardship for farmers and their families. The dominant serotype causing outbreaks between 1998 and 2006 was type O. Using phylogenetic analysis, type O isolated viruses were divided into two topotypes: South East Asia (SEA) and the Middle East-South Asia (ME-SA). Type A virus was reported only in 2003 and 2006 and type Asia 1 only in 1996 and 1998. Crown Copyright (C) 2009 Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:178 / 183
页数:6
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