A chromatographic separation method of verapamil enandomers by HFLC

被引：0

作者：

Adoui, A. ^{[1
]}

Fegas, R. ^{[1
]}

Hamdi, A. ^{[1
]}

Veuthy, J. L. ^{[1
]}

Siouffi, A. M. ^{[1
]}

机构：

[1] USTHB, Fac Chim, Algiers, Algeria

来源：

ASIAN JOURNAL OF CHEMISTRY | 2006年 / 18卷 / 03期

关键词：

verapamil; alpha-AGP column; D-7000; HSM;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this work, a chromatographic HPLC method has been developed to separate enantiomers of calcium channel blocker verapamil using a narrow-bore AGP column and a weak flow rate. The method is reproducible and accurate.

引用

页码：1835 / 1838

页数：4

共 11 条

[1] ASAFAADJAYE BB, 1998, J CHROMATOGR, V707, P169
[2] Bhatti MM, 1997, BIOPHARM DRUG DISPOS, V18, P387, DOI 10.1002/(SICI)1099-081X(199707)18:5<387::AID-BDD26>3.0.CO
[3] 2-X
[4] FAUBRY A, 1993, CHIRALITY, V5, P84
[5] FORD SM, 1995, J CHROMATOGR, V663, P91
[6] Simultaneous determination of verapamil and norverapamil in biological samples by high-performance liquid chromatography using ultraviolet detection
Garcia, MA
Aramayona, JJ
Bregante, MA
Fraile, LJ
Solans, C
[J]. JOURNAL OF CHROMATOGRAPHY B, 1997, 693 (02): : 377 - 382
[7] Simultaneous quantification of the enantiomers of verapamil and its N-demethylated metabolite in human plasma using liquid chromatography-tandem mass spectrometry
Hedeland, M
Fredriksson, E
Lennernäs, H
Bondesson, U
[J]. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2004, 804 (02): : 303 - 311
[8] CHARACTERIZATION OF A CHIRAL-AGP CAPILLARY COLUMN COUPLED TO A MICRO SAMPLE-ENRICHMENT SYSTEM WITH UV AND ELECTROSPRAY MASS-SPECTROMETRIC DETECTION
HERMANSSON, J
HERMANSSON, I
[J]. JOURNAL OF CHROMATOGRAPHY, 1993, 631 (1-2): : 79 - 90
[9] RASMYMAS AK, 1992, J LIQ CHROMATOGR, V15, P3013
[10] A validated method for the determination of verapamil and norverapamil in human plasma
Sawicki, W
[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2001, 25 (3-4) : 689 - 695

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