Switchable cholesterol recognition system with Diels-Alder reaction using molecular imprinting technique on self-assembled monolayer

被引：7
作者：
Shin, Min Jae [1 ]
Kim, Minhee [2 ]
Shin, Jae Sup [2 ]
机构：
[1] Semyung Univ, Dept Cosmet & Biotechnol, Jecheon, South Korea
[2] Chungbuk Natl Univ, Dept Chem, Cheongju 28644, Chungbuk, South Korea
来源：
POLYMER INTERNATIONAL | 2019年 / 68卷 / 10期
基金：
新加坡国家研究基金会;
关键词：
molecular imprinting; self-assembled monolayer; switchable recognition system; Diels-Alder reaction; cholesterol; SYNTHETIC-POLYMERS; SELECTIVE ADSORPTION; SENSING CAPABILITY; QUANTUM DOTS; BISPHENOL-A; SURFACE; SILICA;
D O I：
10.1002/pi.5877
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Molecular imprinting was conducted using a method to form a polymeric coating on a self-assembled monolayer (SAM). This molecular imprinting system was able to obtain an on-off function using the Diels-Alder reaction. Cholesterol was used as a target compound and the SAM was formed using thiol compound on a gold plate. Epoxy resin was used to form the polymeric coating. Covalent bonding method was used in molecular imprinting. The formed molecular imprinting system recognized cholesterol better than analogs of cholesterol. Epoxy resin curing agent with furan group was synthesized to form the molecular imprinting system. Using the Diels-Alder reaction between the furan group and phenylmaleimide, this molecular imprinting system offers a switchable function. (c) 2019 Society of Chemical Industry
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收藏
页码：1722 / 1728
页数：7
相关论文
共 42 条
[21]   Combined Layer/Particle Approaches in Surface Molecular Imprinting of Proteins: Signal Enhancement and Competition [J].
Nam Van Ho Phan ;
Sussitz, Hermann F. ;
Ladenhauf, Eva ;
Pum, Dietmar ;
Lieberzeit, Peter A. .
SENSORS, 2018, 18 (01)
[22]   AN INFRARED SPECTROSCOPIC INVESTIGATION OF THE CURING REACTIONS OF THE EPON-828 META-PHENYLENEDIAMINE SYSTEM [J].
SCHIERING, DW ;
KATON, JE ;
DRZAL, LT ;
GUPTA, VB .
JOURNAL OF APPLIED POLYMER SCIENCE, 1987, 34 (07) :2367-2375
[23]   Electrochemically synthesized polymers in molecular imprinting for chemical sensing [J].
Sharma, Piyush S. ;
Pietrzyk-Le, Agnieszka ;
D'Souza, Francis ;
Kutner, Wlodzimierz .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2012, 402 (10) :3177-3204
[24]   Cholesterol recognition system by molecular imprinting on self-assembled monolayer [J].
Shin, Min Jae ;
Shin, Young Jae ;
Shin, Jae Sup .
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2018, 559 :365-371
[25]   Sensing capability of molecularly imprinted self-assembled monolayer fabricated using dithiol compound [J].
Shin, Min Jae ;
Shin, Young Jae ;
Shin, Jae Sup .
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 2014, 20 (01) :91-95
[26]   Recognizing Amino Acid Chirality with Surface-Imprinted Polymers Prepared in W/O Emulsions [J].
Shin, Min Jae ;
Shin, Young Jae ;
Hwang, Seung Won ;
Shin, Jae Sup .
INTERNATIONAL JOURNAL OF POLYMER SCIENCE, 2013, 2013
[27]   Sensing Capability of Molecularly Imprinted Self-Assembled Monolayer Using Terphenylpropanethiol [J].
Shin, Min Jae ;
Yang, Minhee ;
Shin, Jae Sup .
PARTICULATE SCIENCE AND TECHNOLOGY, 2012, 30 (06) :543-552
[28]   Sensing capability of molecularly imprinted self-assembled monolayer [J].
Shin, Min Jae ;
Hong, Won Hi .
BIOCHEMICAL ENGINEERING JOURNAL, 2011, 54 (01) :57-61
[29]   Challenges for the effective molecular imprinting of proteins [J].
Verheyen, Ellen ;
Schillemans, Joris P. ;
van Wijk, Martin ;
Demeniex, Marie-Astrid ;
Hennink, Wim E. ;
van Nostrum, Cornelus F. .
BIOMATERIALS, 2011, 32 (11) :3008-3020
[30]  
VLADIMIROV LV, 1988, MIKROCHIM ACTA, V1, P329
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