Regulatory T cells and B cells: implication on autoimmune diseases

被引：2
|
作者：
Wang, Ping [1 ]
Zheng, Song Guo [2 ,3 ]
机构：
[1] Nanjing Med Univ, Affiliated Hosp 1, Div Liver Transplantat Surg, Nanjing 210029, Jiangsu, Peoples R China
[2] Penn State Univ, Hershey Coll Med, Dept Med, Div Rheumatol, Hershey, PA 17033 USA
[3] Tongji Univ, Shanghai East Hosp, Inst Immunol, Shanghai 200120, Peoples R China
来源：
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY | 2013年 / 6卷 / 12期
关键词：
Treg; Foxp3; B cells; antibodies; autoimmune diseases; TGF-BETA; CUTTING EDGE; RETINOIC ACID; TREG CELLS; EX-VIVO; SUPPRESS; IL-2; FOXP3; CD4(+); TH17;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The regulatory T (Treg) cells play an important role in the maintenance of homeostasis and the prevention of autoimmune diseases. Although most studies are focusing on the role of Treg cells in T cells and T cells-mediated diseases, these cells also directly affect B cells and other non-T cells. This manuscript updates the role of Treg cells on the B cells and B cell-mediated diseases. In addition, the mechanisms whereby Treg cells suppress B cell responses have been discussed.
引用
收藏
页码：2668 / 2674
页数：7
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