Beckmann Rearrangement of Cyclohexanone Oxime in a Microreactor Setup with Internal Recirculation

被引：11

作者：

Zuidhof, Niek T. ^{[1
]}

de Croon, Mart H. J. M. ^{[1
]}

Schouten, Jaap C. ^{[1
]}

Tinge, Johan T. ^{[2
]}

机构：

[1] Eindhoven Univ Technol, Dept Chem Engn & Chem, Lab Chem Reactor Engn, NL-5600 MB Eindhoven, Netherlands

[2] R&D BV Ind Chem, DSM Chem Technol, Geleen, Netherlands

来源：

CHEMICAL ENGINEERING & TECHNOLOGY | 2013年 / 36卷 / 08期

关键词：

E-Caprolactam; Beckmann rearrangement; Cyclooctane solution; Internal recirculation; EPSILON-CAPROLACTAM;

D O I：

10.1002/ceat.201300088

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Beckmann rearrangement of cyclohexanone oxime dissolved in cyclooctane with oleum to epsilon-caprolactam was demonstrated in a microreactor setup with internal recirculation operated in continuous mode. The core of the setup comprised a 316 stainless-steel micromixer consisting of 17 split-and-recombine units connected to a delay loop, a 316 stainless-steel microchannel reactor with an internal diameter of 0.250 mm and a length of 0.50 m. At 100 degrees C, the conversion of cyclohexanone oxime was complete and the selectivity towards epsilon-caprolactam was approximately 99 %. The solvent cyclooctane reduces the observed purity of the produced oleum/epsilon-caprolactam. This reduction in purity might be a severe hurdle for usage of a solvent on the industrial scale in the Beckmann rearrangement of cyclohexanone oxime in oleum to epsilon-caprolactam.

引用

页码：1387 / 1394

页数：8

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