A concise total synthesis of brasiliquinones B and C and 3-deoxyrabelomycin

被引：32

作者：

Mal, D ^{[1
]}

Roy, HN ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Kharagpur 721302, W Bengal, India

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 21期

关键词：

D O I：

10.1039/a905667j

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of brasiliquinones B and C, 2 and 3 and 3-deoxyrabelomycin 4a has been accomplished in 6-7 steps from the common precursor 18b. The key naphthalenones 6 were prepared in 5 steps from tetralone 17 in a regioselective manner. Anionic annulation of cyanophthalide 7c with 6 readily provided tetracyclic precursors 5 in excellent yields, sunlight-promoted photooxidation of which led to the synthesis of the title compounds.

引用

页码：3167 / 3171

页数：5

共 26 条

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