Desmoid tumor: A focus set on a challenging but understudied rare disease

被引：2

作者：

Kasper, Bernd ^{[1
]}

机构：

[1] Heidelberg Univ, Univ Mannheim, Med Ctr, Sarcoma Unit,Interdisciplinary Tumor Ctr Mannheim, Theodor Kutzer Ufer 1-3, D-68167 Mannheim, Germany

来源：

CANCER | 2019年 / 125卷 / 15期

关键词：

autophagy inhibition; desmoid tumor; medical therapy; mutational analysis; sorafenib; SARCOMA PATIENTS EURONET; EUROPEAN ORGANIZATION; PHASE-II; FIBROMATOSIS; IMATINIB; MUTATION; MANAGEMENT; RECURRENCE; SORAFENIB; TISSUE;

D O I：

10.1002/cncr.32119

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This editorial highlights current developments and new paradigms in the management of desmoid tumor patients as developed by the Desmoid Tumor Working Group. The article "Autophagy Inhibition Overcomes Sorafenib Resistance in S45F-Mutated Desmoid Tumors" is put into perspective regarding a new emerging drug, sorafenib, which is proven to be active in desmoid tumor in a recent phase 3 trial.

引用

页码：2532 / 2533

页数：2

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