Lignin Valorization: Improving Lignin Processing in the Biorefinery

被引：3182

作者：

Ragauskas, Arthur J. ^{[1
]}

Beckham, Gregg T. ^{[2
,3
]}

Biddy, Mary J. ^{[2
,3
]}

Chandra, Richard ^{[4
]}

Chen, Fang ^{[5
]}

Davis, Mark F. ^{[6
,7
]}

Davison, Brian H. ^{[8
]}

Dixon, Richard A. ^{[5
]}

Gilna, Paul ^{[8
]}

Keller, Martin ^{[9
]}

Langan, Paul ^{[10
]}

Naskar, Amit K. ^{[11
]}

Saddler, Jack N. ^{[4
]}

Tschaplinski, Timothy J. ^{[8
]}

Tuskan, Gerald A. ^{[8
]}

Wyman, Charles E. ^{[12
,13
]}

机构：

[1] Georgia Inst Technol, Inst Paper Sci & Technol, Sch Chem & Biochem, BioEnergy Sci Ctr, Atlanta, GA 30332 USA

[2] Natl Renewable Energy Lab, Natl Bioenergy Ctr, Golden, CO 80402 USA

[3] Natl Renewable Energy Lab, Natl Adv Biofuels Consortium, Golden, CO 80402 USA

[4] Univ British Columbia, Dept Wood Sci, Vancouver, BC V6T 1Z4, Canada

[5] Univ N Texas, Dept Biol Sci, BioEnergy Sci Ctr, Denton, TX 76203 USA

[6] Natl Renewable Energy Lab, BioEnergy Sci Ctr, Golden, CO 80402 USA

[7] Natl Renewable Energy Lab, Natl Adv Biofuels Consortium, Golden, CO 80402 USA

[8] Oak Ridge Natl Lab, BioEnergy Sci Ctr, Biosci Div, Oak Ridge, TN 37831 USA

[9] Oak Ridge Natl Lab, Energy & Environm Sci Directorate, Oak Ridge, TN 37831 USA

[10] Oak Ridge Natl Lab, Biol & Soft Matter Div, Oak Ridge, TN 37831 USA

[11] Oak Ridge Natl Lab, Mat Sci & Technol Div, Oak Ridge, TN 37831 USA

[12] Univ Calif Riverside, BioEnergy Sci Ctr, Ctr Environm Res & Technol, Riverside, CA 92507 USA

[13] Univ Calif Riverside, Dept Chem & Environm Engn, Riverside, CA 92507 USA

来源：

SCIENCE | 2014年 / 344卷 / 6185期

关键词：

CINNAMYL ALCOHOL-DEHYDROGENASE; CELL-WALL COMPOSITION; CARBON-FIBER; IONIC LIQUID; BIOSYNTHESIS PERTURBATIONS; LIGNOCELLULOSIC BIOMASS; CARBOHYDRATE COMPLEXES; PRETREATMENT; ETHANOL; PYROLYSIS;

D O I：

10.1126/science.1246843

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Research and development activities directed toward commercial production of cellulosic ethanol have created the opportunity to dramatically increase the transformation of lignin to value-added products. Here, we highlight recent advances in this lignin valorization effort. Discovery of genetic variants in native populations of bioenergy crops and direct manipulation of biosynthesis pathways have produced lignin feedstocks with favorable properties for recovery and downstream conversion. Advances in analytical chemistry and computational modeling detail the structure of the modified lignin and direct bioengineering strategies for future targeted properties. Refinement of biomass pretreatment technologies has further facilitated lignin recovery, and this coupled with genetic engineering will enable new uses for this biopolymer, including low-cost carbon fibers, engineered plastics and thermoplastic elastomers, polymeric foams, fungible fuels, and commodity chemicals.

引用

页码：709 / +

页数：11

共 127 条

[1] Bimetallic catalysts for upgrading of biomass to fuels and chemicals [J].

Alonso, David Martin ;

Wettstein, Stephanie G. ;

Dumesic, James A. .

CHEMICAL SOCIETY REVIEWS, 2012, 41 (24) :8075-8098

[2] Vanillin production from lignin oxidation in a batch reactor [J].

Araujo, Jose D. P. ;

Grande, Carlos A. ;

Rodrigues, Alirio E. .

CHEMICAL ENGINEERING RESEARCH & DESIGN, 2010, 88 (8A) :1024-1032

[3] Integrated analysis of hydrothermal flow through pretreatment [J].

Archambault-Leger, Veronique ;

Shao, Xiongjun ;

Lynd, Lee R. .

BIOTECHNOLOGY FOR BIOFUELS, 2012, 5

[4]

ARGYROPOULOS D, 2013, Patent No. 20130255216

[5] Recent advances in low-cost carbon fiber manufacture from lignin [J].

Baker, Darren A. ;

Rials, Timothy G. .

JOURNAL OF APPLIED POLYMER SCIENCE, 2013, 130 (02) :713-728

[6] Quantification of lignin-carbohydrate linkages with high-resolution NMR spectroscopy [J].

Balakshin, Mikhail ;

Capanema, Ewellyn ;

Gracz, Hanna ;

Chang, Hou-min ;

Jameel, Hasan .

PLANTA, 2011, 233 (06) :1097-1110

[7] Inhibition of cellulase, xylanase and β-glucosidase activities by softwood lignin preparations [J].

Berlin, Alex ;

Balakshin, Mikhail ;

Gilkes, Neil ;

Kadla, John ;

Maximenko, Vera ;

Kubo, Satoshi ;

Saddler, Jack .

JOURNAL OF BIOTECHNOLOGY, 2006, 125 (02) :198-209

[8] Lignin biosynthesis [J].

Boerjan, W ;

Ralph, J ;

Baucher, M .

ANNUAL REVIEW OF PLANT BIOLOGY, 2003, 54 :519-546

[9] Disruption of Mediator rescues the stunted growth of a lignin-deficient Arabidopsis mutant [J].

Bonawitz, Nicholas D. ;

Kim, Jeong Im ;

Tobimatsu, Yuki ;

Ciesielski, Peter N. ;

Anderson, Nickolas A. ;

Ximenes, Eduardo ;

Maeda, Junko ;

Ralph, John ;

Donohoe, Bryon S. ;

Ladisch, Michael ;

Chapple, Clint .

NATURE, 2014, 509 (7500) :376-+

[10] Can genetic engineering of lignin deposition be accomplished without an unacceptable yield penalty? [J].

Bonawitz, Nicholas D. ;

Chapple, Clint .

CURRENT OPINION IN BIOTECHNOLOGY, 2013, 24 (02) :336-343

← 1 2 3 4 5 6 7 8 9 10 →