A facile protocol for the synthesis of 3-aminoimidazo-fused heterocycles via the Groebke-Blackburn-Bienayme reaction under catalyst-free and solvent-free conditions

被引：96
|
作者：
Vidyacharan, Shinde [1 ]
Shinde, Anand H. [1 ]
Satpathi, Bishnupada [1 ]
Sharada, Duddu S. [1 ]
机构：
[1] Indian Inst Technol, Dept Chem, Hyderabad 502205, Andhra Pradesh, India
来源：
GREEN CHEMISTRY | 2014年 / 16卷 / 03期
关键词：
MULTICOMPONENT REACTIONS; 3-COMPONENT CONDENSATION; REGIOSELECTIVE SYNTHESIS; ANNULATED PYRIDINES; BENIGN SYNTHESIS; CHEMISTRY; PYRAZINES; CONSTRUCTION; PYRIMIDINES; INHIBITORS;
D O I：
10.1039/c3gc42130a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A one-pot catalyst, solvent, work-up and column free synthesis of 3-aminoimidazo-fused heterocycles by a three-component reaction of a 2-aminoheterocycle, aldehyde, and isocyanide is presented. This efficient and green protocol has the advantages of environmental friendliness, high yields and operational simplicity.
引用
收藏
页码：1168 / 1175
页数：8
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