In vitro susceptibilities to amphotericin B, itraconazole, and miconazole of filamentous fungi isolated from patients with cystic fibrosis

被引：21

作者：

Hennequin, C

Benailly, N

Silly, C

Sorin, M

Scheinmann, P

Lenoir, G

Gaillard, JL

Berche, P

机构：

[1] HOP NECKER ENFANTS MALAD, SERV PEDIAT GEN, F-75015 PARIS, FRANCE

[2] HOP NECKER ENFANTS MALAD, SERV PNEUMOL PEDIAT, F-75015 PARIS, FRANCE

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1997年 / 41卷 / 09期

关键词：

D O I：

10.1128/AAC.41.9.2064

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The antimicrobial activities of amphotericin B, itraconazole, and miconazole against 101 filamentous fungi from patients with cystic fibrosis were tested by a reproducible microdilution method. Itraconazole was very active against Aspergillus species and Scedosporium species (MIC at which 90% of the isolates were inhibited [MIC90], 0.06 to 0.5 mg/liter), whereas amphotericin B was Less effective (MIC90, 0.5 to 8 mg/liter).

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页码：2064 / 2066

页数：3

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