Novel Treatments of Autosomal Dominant Polycystic Kidney Disease

被引:5
作者
Mahnensmith, Rex L. [1 ]
机构
[1] Yale Univ, Sch Med, Dept Internal Med, New Haven, CT 06519 USA
来源
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY | 2014年 / 9卷 / 05期
关键词
ADPKD; vasopressin antagonists; mTOR inhibitors; somatostatin analogs; statins; ANGIOTENSIN-ALDOSTERONE SYSTEM; LONG-ACTING SOMATOSTATIN; SIROLIMUS THERAPY; CLINICAL-TRIAL; LIVER-DISEASE; RENAL VOLUME; CYST GROWTH; VASOPRESSIN; PROGRESSION; ADPKD;
D O I
10.2215/CJN.02480314
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:831 / 836
页数:6
相关论文
共 43 条
[1]   Low-Dose Rapamycin ( Sirolimus) Effects in Autosomal Dominant Polycystic Kidney Disease: An Open-Label Randomized Controlled Pilot Study [J].
Braun, William E. ;
Schold, Jesse D. ;
Stephany, Brian R. ;
Spirko, Rita A. ;
Herts, Brian R. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2014, 9 (05) :881-888
[2]   Effect of Pravastatin on Total Kidney Volume, Left Ventricular Mass Index, and Microalbuminuria in Pediatric Autosomal Dominant Polycystic Kidney Disease [J].
Cadnapaphornchai, Melissa A. ;
George, Diana M. ;
McFann, Kim ;
Wang, Wei ;
Gitomer, Berenice ;
Strain, John D. ;
Schrier, Robert W. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2014, 9 (05) :889-896
[3]   Prospective Change in Renal Volume and Function in Children with ADPKD [J].
Cadnapaphornchai, Melissa A. ;
McFann, Kim ;
Strain, John D. ;
Masoumi, Amirali ;
Schrier, Robert W. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2009, 4 (04) :820-829
[4]   Effect of longacting somatostatin analogue on kidney and cyst growth in autosomal dominant polycystic kidney disease (ALADIN): a randomised, placebo-controlled, multicentre trial [J].
Caroli, Anna ;
Perico, Norberto ;
Perna, Annalisa ;
Antiga, Luca ;
Brambilla, Paolo ;
Pisani, Antonio ;
Visciano, Bianca ;
Imbriaco, Massimo ;
Messa, Piergiorgio ;
Cerutti, Roberta ;
Dugo, Mauro ;
Cancian, Luca ;
Buongiorno, Erasmo ;
De Pascalis, Antonio ;
Gaspari, Flavio ;
Carrara, Fabiola ;
Rubis, Nadia ;
Prandini, Silvia ;
Remuzzi, Andrea ;
Remuzzi, Giuseppe ;
Ruggenenti, Piero .
LANCET, 2013, 382 (9903) :1485-1495
[5]   THE RENIN-ANGIOTENSIN ALDOSTERONE SYSTEM AND AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY-DISEASE [J].
CHAPMAN, AB ;
JOHNSON, A ;
GABOW, PA ;
SCHRIER, RW .
NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (16) :1091-1096
[6]   Renal structure in early autosomal-dominant polycystic kidney disease (ADPKD): The Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP) cohort [J].
Chapman, AB ;
Guay-Woodford, LM ;
Grantham, JJ ;
Torres, VE ;
Bae, KT ;
Baumgarten, DA ;
Kenney, PJ ;
King, BF ;
Glockner, JF ;
Wetzel, LH ;
Brummer, ME ;
O'Neill, WC ;
Robbin, ML ;
Bennett, WM ;
Klahr, S ;
Hirschman, GH ;
Kimmel, PL ;
Thompson, PA ;
Miller, JP .
KIDNEY INTERNATIONAL, 2003, 64 (03) :1035-1045
[7]   Hypertension in Autosomal Dominant Polycystic Kidney Disease [J].
Chapman, Arlene B. ;
Stepniakowski, Konrad ;
Rahbari-Oskoui, Frederic .
ADVANCES IN CHRONIC KIDNEY DISEASE, 2010, 17 (02) :153-163
[8]   The HALT Polycystic Kidney Disease Trials: Design and Implementation [J].
Chapman, Arlene B. ;
Torres, Vicente E. ;
Perrone, Ronald D. ;
Steinman, Theodore I. ;
Bae, Kyongtae T. ;
Miller, J. Philip ;
Miskulin, Dana C. ;
Oskoui, Frederic Rahbari ;
Masoumi, Arnirali ;
Hogan, Marie C. ;
Winklhofer, Franz T. ;
Braun, William ;
Thompson, Paul A. ;
Meyers, Catherine M. ;
Kelleher, Cass ;
Schrier, Robert W. .
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2010, 5 (01) :102-109
[9]   Osmoregulation, vasopressin, and cAMP signaling in autosomal dominant polycystic kidney disease [J].
Devuyst, Olivier ;
Torres, Vicente E. .
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION, 2013, 22 (04) :459-470
[10]  
ELZINGA LW, 1992, J AM SOC NEPHROL, V2, P1219