Obesity and GERD

被引:187
作者
Chang, Paul [1 ]
Friedenberg, Frank [1 ]
机构
[1] Temple Univ, Sch Med, Gastroenterol Sect, Philadelphia, PA 19122 USA
关键词
Obesity; Gastroesophageal reflux disease; Barrett esophagus; Waist-to-hip ratio; Adiponectin; Leptin; GASTROESOPHAGEAL-REFLUX DISEASE; BODY-MASS INDEX; ESOPHAGEAL MOTILITY DISORDERS; Y GASTRIC BYPASS; INDEPENDENT RISK-FACTOR; POPULATION-BASED COHORT; MORBIDLY OBESE; BARRETTS-ESOPHAGUS; EROSIVE ESOPHAGITIS; ABDOMINAL OBESITY;
D O I
10.1016/j.gtc.2013.11.009
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Epidemiologic data have demonstrated that obesity is an important risk factor for the development of gastroesophageal reflux disease (GERD). There is also accumulating data that obesity is associated with complications related to longstanding reflux such as erosive esophagitis, Barrett esophagus, and esophageal adenocarcinoma. Central obesity, rather than body mass index, appears to be more closely associated with these complications. Surgical data are confounded by the concomitant repair of prevalent hiatal hernias in many patients.
引用
收藏
页码:161 / +
页数:14
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