Basal Forebrain Cholinergic System and Orexin Neurons: Effects on Attention

被引：105

作者：

Villano, Ines ^{[1
]}

Messina, Antonietta ^{[1
]}

Valenzano, Anna ^{[2
]}

Moscatelli, Fiorenzo ^{[2
,3
]}

Esposito, Teresa ^{[1
]}

Monda, Vincenzo ^{[1
]}

Esposito, Maria ^{[4
]}

Precenzano, Francesco ^{[4
]}

Carotenuto, Marco ^{[4
,5
]}

Viggiano, Andrea ^{[6
]}

Chieffi, Sergio ^{[2
]}

Cibelli, Giuseppe ^{[2
]}

Monda, Marcellino ^{[1
]}

Messina, Giovanni ^{[1
,2
]}

机构：

[1] Univ Naples 2, Dept Expt Med, Naples, Italy

[2] Univ Foggia, Dept Clin & Expt Med, Foggia, Italy

[3] Univ Rome Foro Italico, Dept Motor Human & Hlth Sci, Rome, Italy

[4] Univ Naples 2, Dept Mental Hlth Phys & Prevent Med, Naples, Italy

[5] Univ Naples 2, NBG, Clin Child & Adolescent Neuropsychiat, Dept Mental Phys Hlth & Prevent Med, Naples, Italy

[6] Univ Salerno, Scuola Med Salernitana, Dept Med Surg & Dent, Salerno, Italy

来源：

FRONTIERS IN BEHAVIORAL NEUROSCIENCE | 2017年 / 11卷

关键词：

attention; orexin; basal forebrain; lateral hypothalamus; acetylcholine; CORTICAL ACETYLCHOLINE-RELEASE; MELANIN-CONCENTRATING HORMONE; HYPOCRETIN OREXIN; LOCUS-COERULEUS; IMMUNOHISTOCHEMICAL EVIDENCE; HYPOTHALAMIC NEURONS; PREFRONTAL CORTEX; SLEEP-DEPRIVATION; CEREBRAL-CORTEX; A HYPOCRETIN-1;

D O I：

10.3389/fnbeh.2017.00010

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The basal forebrain (BF) cholinergic system has an important role in attentive functions. The cholinergic system can be activated by different inputs, and in particular, by orexin neurons, whose cell bodies are located within the postero-lateral hypothalamus. Recently the orexin-producing neurons have been proved to promote arousal and attention through their projections to the BE The aim of this review article is to summarize the evidence showing that the orexin system contributes to attentional processing by an increase in cortical acetylcholine release and in cortical neurons activity.

引用

页数：11

共 119 条

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