Long-Term Effective Thalamic Deep Brain Stimulation for Neuropathic Tremor in Two Patients with Charcot-Marie-Tooth Disease

被引：2

作者：

Cabanes-Martinez, Lidia ^{[1
,2
]}

Del Alamo de Pedro, Marta ^{[1
,3
]}

de Blas Beorlegui, Gema ^{[2
]}

Regidor Bailly-Bailliere, Ignacio ^{[1
,2
]}

机构：

[1] Hosp Univ Ramon y Cajal, Funct Neurosurg Unit, Carretera Colmenar Viejo,Km 9-1, ES-28034 Madrid, Spain

[2] Hosp Univ Ramon y Cajal, Clin Neurophysiol Dept, Madrid, Spain

[3] Hosp Univ Ramon y Cajal, Neurosurg Dept, Madrid, Spain

来源：

STEREOTACTIC AND FUNCTIONAL NEUROSURGERY | 2017年 / 95卷 / 02期

关键词：

Tremor; Polyneuropathies; Deep brain stimulation; Neurophysiology; Ventral intermediate nucleus; DEMYELINATING NEUROPATHY; MOVEMENT-DISORDERS; FOLLOW-UP; NUCLEUS;

D O I：

10.1159/000457963

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Background: It has been described that many Charcot-Marie-Tooth syndrome type 2 patients are affected by a very disabling type of tremor syndrome, the pathophysiology of which remains unclear. Deep brain stimulation (DBS) has been successfully applied to treat most types of tremors by implanting electrodes in the ventral intermediate nucleus of the thalamus (Vim). Methods: We used DBS applied to the Vim in 2 patients with severe axonal inherited polyneuropathies who developed a disabling tremor. Results: Both patients responded positively to stimulation, with a marked reduction of the tremor and with an improvement of their quality of life. Conclusion: We report 2 cases of tremor associated with a hereditary neuropathy with a good response to DBS. (C) 2017 S. Karger AG, Basel

引用

页码：102 / 106

页数：5

共 20 条

[1] Tremor associated with benign IgM paraproteinaemic neuropathy [J].

Bain, PG ;

Britton, TC ;

Jenkins, IH ;

Thompson, PD ;

Rothwell, JC ;

Thomas, PK ;

Brooks, DJ ;

Marsden, CD .

BRAIN, 1996, 119 :789-799

[2] Deep Brain Stimulation of the Ventral Intermediate Thalamic Nucleus for Severe Tremor in Anti-MAG Neuropathy [J].

Bayreuther, Caroline ;

Delmont, Emilien ;

Borg, Michel ;

Fontaine, Denys .

MOVEMENT DISORDERS, 2009, 24 (14) :2157-2158

[3] Chronic electrical stimulation of the ventralis intermedius nucleus of the thalamus as a treatment of movement disorders [J].

Benabid, AL ;

Pollak, P ;

Gao, DM ;

Hoffmann, D ;

Limousin, P ;

Gay, E ;

Payen, I ;

Benazzouz, A .

JOURNAL OF NEUROSURGERY, 1996, 84 (02) :203-214

[4]

BENABID AL, 1993, ACTA NEUROCHIR, P39

[5]

Boecker H, 1998, MOVEMENT DISORD, V13, P64

[6] The genetic convergence of charcot-marie-tooth disease types 1 and 2 and the role of genetics in sporadic neuropathy [J].

Boerkoel C.F. ;

Takashima H. ;

Lupski J.R. .

Current Neurology and Neuroscience Reports, 2002, 2 (1) :70-77

[7] Effective thalamic deep brain stimulation for neuropathic tremor in a patient with severe demyelinating neuropathy [J].

Breit, S. ;

Waechter, T. ;

Schoels, L. ;

Gasser, T. ;

Naegele, T. ;

Freudenstein, D. ;

Krueger, R. .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2009, 80 (02) :235-236

[8] HEREDITARY MOTOR SENSORY NEUROPATHY AND MOVEMENT-DISORDERS [J].

CARDOSO, FEC ;

JANKOVIC, J .

MUSCLE & NERVE, 1993, 16 (09) :904-910

[9] Pathophysiology of nonparkinsonian tremors [J].

Deuschl, G ;

Bergman, H .

MOVEMENT DISORDERS, 2002, 17 :S41-S48

[10] DEEP BRAIN STIMULATION: 12 YEARS' EXPERIENCE AND 150 PATIENTS TREATED WITH A FOLLOW-UP OF OVER A YEAR [J].

Figueiras-Mendez, R. ;

Magarinos-Ascone, C. ;

Regidor, I. ;

del Alamo-De Pedro, M. ;

Cabanes-Martinez, L. ;

Gomez-Galan, M. .

REVISTA DE NEUROLOGIA, 2009, 49 (10) :511-516

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