Microenvironment-dependent resistance to ABT-737 in chronic lymphocytic leukemia Response

被引：1
|
作者：
Butterworth, Michael [1 ]
Vogler, Meike [1 ]
Dyer, Martin J. S. [1 ]
Cohen, Gerald M. [1 ]
机构：
[1] Univ Leicester, MRC Toxicol Unit, Leicester LE1 9HN, Leics, England
来源：
BLOOD | 2009年 / 114卷 / 12期
关键词：
PROLIFERATION; INHIBITORS; APOPTOSIS; LYMPHOMA; BALANCE; CXCR4; CELLS;
D O I：
10.1182/blood-2009-07-232926
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：2561 / 2562
页数：4
相关论文
共 50 条
  • [21] Bcl-2 phosphorylation confers resistance on chronic lymphocytic leukaemia cells to the BH3 mimetics ABT-737, ABT-263 and ABT-199 by impeding direct binding
    Song, Ting
    Chai, Gaobo
    Liu, Yubo
    Yu, Xiaoyan
    Wang, Ziqian
    Zhang, Zhichao
    BRITISH JOURNAL OF PHARMACOLOGY, 2016, 173 (03) : 471 - 483
  • [22] ABT-737 Cooperates in a Strong Synergism with Tyrosine Kinase Inhibitors to Induce Apoptosis of Chronic Myeloid Leukemia Cells
    Belloc, Francis
    Airiau, Kelly
    Jeanneteau, Marie
    Mahon, Francois-Xavier
    BLOOD, 2009, 114 (22) : 1257 - 1257
  • [23] ABT-737 is a useful component of combinatory chemotherapies for chronic myeloid leukaemias with diverse drug-resistance mechanisms
    Kuroda, Junya
    Kimura, Shinya
    Andreeff, Michael
    Ashihara, Eishi
    Kamitsuji, Yuri
    Yokota, Asumi
    Kawata, Eri
    Takeuchi, Miki
    Tanaka, Ruriko
    Murotani, Yoshihide
    Matsumoto, Yosuke
    Tanaka, Hideo
    Strasser, Andreas
    Taniwaki, Masafumi
    Maekawa, Taira
    BRITISH JOURNAL OF HAEMATOLOGY, 2008, 140 (02) : 181 - 190
  • [24] ABT-737 resistance in B-cells isolated from chronic lymphocytic leukemia patients and leukemia cell lines is overcome by the pleiotropic kinase inhibitor quercetin through Mcl-1 down-regulation
    Russo, Maria
    Spagnuolo, Carmela
    Volpe, Silvestro
    Tedesco, Idolo
    Bilotto, Stefania
    Russo, Gian Luigi
    BIOCHEMICAL PHARMACOLOGY, 2013, 85 (07) : 927 - 936
  • [25] Pro-apoptotic effects on CLL (chronic lymphocytic leukemia) of ABT-737, a novel fully synthetic Bcl-2/Bcl-XL antagonist.
    Kitada, S
    Monosov, E
    Chandler, S
    Avery, ED
    Kipps, TJ
    Rosenberg, SH
    Reed, JC
    BLOOD, 2004, 104 (11) : 272A - 273A
  • [26] ABT-737 ameliorates docetaxel resistance in triple negative breast cancer cell line
    Hwang, Eunjoo
    Hwang, Seong-Hye
    Kim, Jongjin
    Park, Jin Hyun
    Oh, Sohee
    Kim, Young A.
    Hwang, Ki-Tae
    ANNALS OF SURGICAL TREATMENT AND RESEARCH, 2018, 95 (05) : 240 - 248
  • [27] Melatonin Enhances the Effect of ABT-737 in Acute Monocytic Leukemia THP-1 Cells
    Lomovsky, A. I.
    Baburina, Y. L.
    Fadeev, R. S.
    Kobyakova, M. I.
    Lomovskaya, Ya. V.
    Krestinin, R. R.
    Sotnikova, L. D.
    Krestinina, O. V.
    MOLECULAR BIOLOGY, 2024, 58 (01) : 112 - 122
  • [28] MEK1/2 inhibition by binimetinib is effective as a single agent and potentiates the actions of Venetoclax and ABT-737 under conditions that mimic the chronic lymphocytic leukaemia (CLL) tumour microenvironment
    Crassini, Kyle
    Shen, Yandong
    Stevenson, William S.
    Christopherson, Richard
    Ward, Chris
    Mulligan, Stephen P.
    Best, O. Giles
    BRITISH JOURNAL OF HAEMATOLOGY, 2018, 182 (03) : 360 - 372
  • [29] Melatonin Enhances the Effect of ABT-737 in Acute Monocytic Leukemia THP-1 Cells
    A. I. Lomovsky
    Y. L. Baburina
    R. S. Fadeev
    M. I. Kobyakova
    Ya. V. Lomovskaya
    R. R. Krestinin
    L. D. Sotnikova
    O. V. Krestinina
    Molecular Biology, 2024, 58 : 112 - 122
  • [30] C3aR1 Contributed to Acute Myeloid Leukemia Acquired Resistance to ABT-737 and Involved In the Process of AML
    Hu, Shaoyan
    Mirshahidi, Saied
    Bi, Chong-Lei
    Chng, Wee-Joo
    Hsu, Heng-Wei
    Wui, Shui-yan
    Pan, Jian
    Cen, Jian-Nong
    Chen, Chien-Shing
    BLOOD, 2011, 118 (21) : 623 - 623
12345