Microenvironment-dependent resistance to ABT-737 in chronic lymphocytic leukemia Response

被引：1

作者：

Butterworth, Michael ^{[1
]}

Vogler, Meike ^{[1
]}

Dyer, Martin J. S. ^{[1
]}

Cohen, Gerald M. ^{[1
]}

机构：

[1] Univ Leicester, MRC Toxicol Unit, Leicester LE1 9HN, Leics, England

来源：

BLOOD | 2009年 / 114卷 / 12期

关键词：

PROLIFERATION; INHIBITORS; APOPTOSIS; LYMPHOMA; BALANCE; CXCR4; CELLS;

D O I：

10.1182/blood-2009-07-232926

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2561 / 2562

页数：4

共 12 条

[1] Spleen Tyrosine Kinase Is Overexpressed and Represents a Potential Therapeutic Target in Chronic Lymphocytic Leukemia [J].

Buchner, Maike ;

Fuchs, Simon ;

Prinz, Gabriele ;

Pfeifer, Dietmar ;

Bartholome, Kilian ;

Burger, Meike ;

Chevalier, Nina ;

Vallat, Laurent ;

Timmer, Jens ;

Gribben, John G. ;

Jumaa, Hassan ;

Veelken, Hendrik ;

Dierks, Christine ;

Zirlik, Katja .

CANCER RESEARCH, 2009, 69 (13) :5424-5432

[2] CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers [J].

Burger, J. A. ;

Peled, A. .

LEUKEMIA, 2009, 23 (01) :43-52

[3] CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment [J].

Burger, JA ;

Kipps, TJ .

BLOOD, 2006, 107 (05) :1761-1767

[4] Chronic lymphocytic leukemia microenvironment: shifting the balance from apoptosis to proliferation [J].

Deaglio, Silvia ;

Malavasi, Fabio .

HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 (06) :752-756

[5] Lymphoma microenvironment: culprit or innocent? [J].

Herreros, B. ;

Sanchez-Aguilera, A. ;

Piris, M. A. .

LEUKEMIA, 2008, 22 (01) :49-58

[6] PROLIFERATION CENTERS IN B-CELL MALIGNANT-LYMPHOMA, LYMPHOCYTIC (B-CLL) - AN IMMUNOPHENOTYPIC STUDY [J].

SCHMID, C ;

ISAACSON, PG .

HISTOPATHOLOGY, 1994, 24 (05) :445-451

[7] Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity [J].

Smit, Laura A. ;

Hallaert, Delfine Y. H. ;

Spijker, Ren ;

de Goeij, Bart ;

Jaspers, Annelieke ;

Kater, Arnon P. ;

van Oers, Marinus H. J. ;

van Wesel, Carel J. M. ;

Eldering, Eric .

BLOOD, 2007, 109 (04) :1660-1668

[8] The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized [J].

van Delft, Mark F. ;

Wei, Andrew H. ;

Mason, Kylie D. ;

Vandenberg, Cassandra J. ;

Chen, Lin ;

Czabotar, Peter E. ;

Willis, Simon N. ;

Scott, Clare L. ;

Day, Catherine L. ;

Cory, Suzanne ;

Adams, Jerry M. ;

Roberts, Andrew W. ;

Huang, David C. S. .

CANCER CELL, 2006, 10 (05) :389-399

[9] Different forms of cell death induced by putative BCL2 inhibitors [J].

Vogler, M. ;

Weber, K. ;

Dinsdale, D. ;

Schmitz, I. ;

Schulze-Osthoff, K. ;

Dyer, M. J. S. ;

Cohen, G. M. .

CELL DEATH AND DIFFERENTIATION, 2009, 16 (07) :1030-1039

[10] Bcl-2 inhibitors: small molecules with a big impact on cancer therapy [J].

Vogler, M. ;

Dinsdale, D. ;

Dyer, M. J. S. ;

Cohen, G. M. .

CELL DEATH AND DIFFERENTIATION, 2009, 16 (03) :360-367

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