α-Alkylation of Ketones with Secondary Alcohols Catalyzed by Well-Defined Cp*CoIII-Complexes

被引：65

作者：

Chakraborty, Priyanka ^{[1
]}

Gangwar, Manoj Kumar ^{[1
]}

Emayavaramban, Balakumar ^{[1
]}

Manoury, Eric ^{[2
]}

Poli, Rinaldo ^{[2
]}

Sundararaju, Basker ^{[1
]}

机构：

[1] Indian Inst Technol Kanpur, Dept Chem, Kanpur 208016, Uttar Pradesh, India

[2] Univ Toulouse, UPS, INPT, Fine CNRS,LCC, 205 Route Narbonne, F-31077 Toulouse 4, France

来源：

CHEMSUSCHEM | 2019年 / 12卷 / 15期

关键词：

alkylation; cobalt; ketones; secondary alcohols; alpha-alkylation; H BOND FUNCTIONALIZATION; BORROWING HYDROGEN; COBALT; DEHYDROGENATION; CONVERSION; NITRILES; ETHANOL; ESTERS; ACTIVATION; ANNULATION;

D O I：

10.1002/cssc.201900990

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Although alpha-alkylation of ketones with primary alcohols by transition-metal catalysis is well-known, the same process with secondary alcohols is arduous and complicated by self-condensation. Herein a well-defined, high-valence cobalt(III)-catalyst was applied for successful alpha-alkylation of ketones with secondary alcohols. A wide-variety of secondary alcohols, which include cyclic, acyclic, symmetrical, and unsymmetrical compounds, was employed as alkylating agents to produce beta-alkyl aryl ketones.

引用

页码：3463 / 3467

页数：5

共 89 条

[1] Homogeneous Ethanol to Butanol Catalysis-Guerbet Renewed
Aitchison, Hope
Wingad, Richard L.
Wass, Duncan F.
[J]. ACS CATALYSIS, 2016, 6 (10): : 7125 - 7132
[2] Stereoselective Synthesis of Cyclohexanes via an Iridium Catalyzed (5+1) Annulation Strategy
Akhtar, Wasim M.
Armstrong, Roly J.
Frost, James R.
Stevenson, Neil G.
Donohoe, Timothy J.
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 140 (38) : 11916 - 11920
[3] Hydrogen Borrowing Catalysis with Secondary Alcohols: A New Route for the Generation of β-Branched Carbonyl Compounds
Akhtar, Wasim M.
Cheong, Choon Boon
Frost, James R.
Christensen, Kirsten E.
Stevenson, Neil G.
Donohoe, Timothy J.
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2017, 139 (07) : 2577 - 2580
[4] First-Row Transition Metal (De)Hydrogenation Catalysis Based On Functional Pincer Ligands
Alig, Lukas
Fritz, Maximilian
Schneider, Sven
[J]. CHEMICAL REVIEWS, 2019, 119 (04) : 2681 - 2751
[5] [Anonymous], 2014, ANGEW CHEM
[6] [Anonymous], 2007, Angew. Chem.
[7] [Anonymous], 2015, ANGEW CHEM-GER EDIT
[8] The Catalytic Amination of Alcohols
Baehn, Sebastian
Imm, Sebastian
Neubert, Lorenz
Zhang, Min
Neumann, Helfried
Beller, Matthias
[J]. CHEMCATCHEM, 2011, 3 (12) : 1853 - 1864
[9] Iron-catalyzed dehydrogenation reactions and their applications in sustainable energy and catalysis
Balaraman, Ekambaram
Nandakumar, Avanashiappan
Jaiswal, Garima
Sahoo, Manoj K.
[J]. CATALYSIS SCIENCE & TECHNOLOGY, 2017, 7 (15) : 3177 - 3195
[10] Osmium Catalyst for the Borrowing Hydrogen Methodology: α-Alkylation of Arylacetonitriles and Methyl Ketones
Buil, Maria L.
Esteruelas, Miguel A.
Herrero, Juana
Izquierdo, Susana
Pastor, Isidro M.
Yus, Miguel
[J]. ACS CATALYSIS, 2013, 3 (09): : 2072 - 2075

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